59279-37-7

Upstream product

• 50-69-1 D-ribose 
• 122-04-3 4-nitro-benzoyl chloride 
• 1824-96-0 methyl ribofuranoside 

Downstream Products

• 59279-39-9 2,5-anhydro-3,4,6-tri-O-(p-nitrobenzoyl)-D-allononitrile 
• 58706-09-5 methyl 3,5-di-O-(p-nitrobenzoyl)-β-D-ribofuranoside 
• 58706-08-4 methyl 2,5-di-O-(p-nitrobenzoyl)-β-D-ribofuranoside 
• 63527-43-5 2,3,5-p-Nitrobenzoyl-D-ribofuranosylbromid 
• 86042-27-5 1-O-acetyl-2,3,5-tri-O-p-nitrobenzoyl-β-D-ribofuranose 
• 86042-26-4 1-O-acetyl-2,3,5-tri-O-p-nitrobenzoyl-α-D-ribofuranose 

Relevant academic research and scientific papers

IMPROVED SYNTHESIS OF 2,5-ANHYDRO-D-ALLONITRILE

Two types of mixed ester of β-D-ribofuranose were synthesized.The first had the same groups attached to O-1, 2, and 3, and the second had the same groups attached to O-2,3 and 5.The three esters obtained in the highest yields, starting from D-ribose, were then converted into the halides and nitriles.Of the esters studied, the best suited for conversion into the nitrile was 1-O-acetyl-2,3,5-tri-O-p-toluyl-β-D-ribofuranose, which afforded 2,5-anhydro-3,4,6-tri-O-p-toluyl-D-allonitrile in 60percent yield.

Crystalline ribofuranosyl halides and other derivatives and methods for producing same

Methyl-D-ribofuranoside is p-nitrobenzoylated to yield crystalline methyl 2,3,5-tri-O-(p-nitrobenzoyl)-β-D-ribofuranoside which can be used to prepare a stable, crystalline 2,3,5-tri-O-(p-nitrobenzoyl)-β-D-ribofuranosyl bromide which in turn is useful as

Processes for production of a 1-N-(α-hydroxy-Φ-amino alkanoyl)-3-deoxy-5-O-pentafuranosyl neamine and new compounds produced by the same processes

This invention relates to new processes for the production of a 1-N-(α-hydroxy-ω-aminoalkanoyl)-3'-deoxy-5-O-pentofuranosylneamine, including 3'-deoxybutirosins A and B, as a semi-synthetic antibiotic. This invention further relates to new and useful semi-synthetic antibiotics which are produced by the above new processes.