59279-37-7Relevant articles and documents
IMPROVED SYNTHESIS OF 2,5-ANHYDRO-D-ALLONITRILE
El Khadem, Hassan S.,Kawai, Joshua
, p. 131 - 138 (2007/10/02)
Two types of mixed ester of β-D-ribofuranose were synthesized.The first had the same groups attached to O-1, 2, and 3, and the second had the same groups attached to O-2,3 and 5.The three esters obtained in the highest yields, starting from D-ribose, were then converted into the halides and nitriles.Of the esters studied, the best suited for conversion into the nitrile was 1-O-acetyl-2,3,5-tri-O-p-toluyl-β-D-ribofuranose, which afforded 2,5-anhydro-3,4,6-tri-O-p-toluyl-D-allonitrile in 60percent yield.
Processes for production of a 1-N-(α-hydroxy-Φ-amino alkanoyl)-3-deoxy-5-O-pentafuranosyl neamine and new compounds produced by the same processes
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, (2008/06/13)
This invention relates to new processes for the production of a 1-N-(α-hydroxy-ω-aminoalkanoyl)-3'-deoxy-5-O-pentofuranosylneamine, including 3'-deoxybutirosins A and B, as a semi-synthetic antibiotic. This invention further relates to new and useful semi-synthetic antibiotics which are produced by the above new processes.