593-12-4

Usage

Uses

Used in Pharmaceutical Industry:
1-Bromo-8-fluorooctane is used as a synthetic intermediate for the production of various pharmaceutical products, contributing to the development of new medications and therapies.
Used in Research and Development:
In the realm of research and development, 1-Bromo-8-fluorooctane is utilized as a reagent in organic synthesis, particularly for the creation of complex organic molecules, aiding in the advancement of chemical knowledge and innovation.
Used in Organic Synthesis:
1-Bromo-8-fluorooctane is used as a reagent in organic synthesis processes, playing a crucial role in the production of intricate organic compounds that may have various applications across different industries.
Safety Considerations:
Given its classification as a hazardous material, 1-Bromo-8-fluorooctane requires careful handling to prevent harm upon inhalation, ingestion, or skin contact. It should be stored under safety conditions in a cool, dry place, away from direct sunlight and ignition sources, to mitigate risks associated with its use.

InChI:InChI=1/C8H16BrF/c9-7-5-3-1-2-4-6-8-10/h1-8H2

Upstream product

• 4549-32-0 1,8-dibromooctane 
• 50816-19-8 8-bromooctanol 
• 144-55-8 sodium hydrogencarbonate 
• 408-27-5 8-fluoro-octan-1-ol 

Downstream Products

• 88730-57-8 1-<(2-Tetrahydropyranyl)oxy>-12-fluorododec-3-yne 
• 1478-37-1 ω-Fluor-oelsaeure 
• 408-37-7 18‐fluorooctadecanoic acid 

Relevant academic research and scientific papers

Stereochemistry of 10-sulfoxidation catalyzed by a soluble Δ9 desaturase

The stereochemistry of castor stearoyl-ACP Δ9 desaturase-mediated 10-sulfoxidation has been determined. This was accomplished by 19F NMR analysis of a fluorine-tagged product, 18-fluoro-10-thiastearoyl ACP S-oxide, in combination with a chiral solvating agent, (R)-AMA. Sulfoxidation proceeds with the same stereoselectivity as hydrogen removal from the parent stearoyl substrate. These data validate the use of thia probes to determine the stereochemistry and cryptoregiochemistry of desaturase-mediated oxidations.

FLUORINATION OF HALOGENO ALCOHOLS WITH 1,1,2,3,3,3-HEXAFLUOROPROPYL DIETHYLAMINE

Fluorination of halogeno alcohols with 1,1,2,3,3,3-hexafluoropropyl diethylamine (PPDA) was investigated. 2-Bromo-1-fluorobutane was obtained from the reaction of PPDA and 2-bromo-1-butanol (yield 50percent).Similar results were obtained from other alipha

Synthesis of ω-Tritiated and ω-Fluorinated Analogues of the Trail Pheromone of Subterranean Termites

A series of unsaturated ω-fluoro alcohols have been prepared stereoselectively.These simple compounds are structural analogues of the trail pheromone of termites in the genus Reticulitermes.The toxicity of these ω-fluoro alcohols to R. flavipes is maximal for the C12 alcohols, and the attractiveness of these C12 analogues increases in the order saturated alkanol -12-fluoro alcohols and a -nonfluorinated analogue were prepared to examine the catabolism of the pheromone analogues.

Attractant termiticidal compounds, compositions and methods of use therefor

Alpha - fluoro - omega - hydroxy straight chain hydrocarbons are utilized to form attractant termiticidal compositions which are safe and economical for the combatting of termites and related pests.