5931-52-2

Upstream product

• 553-94-6 4-bromo-m-xylene 
• 6737-42-4 1,3-bis-(diphenylphosphino)propane 
• 829-85-6 diphenylphosphane 

Downstream Products

• 590363-05-6 (acetylacetonato)carbonylrhodium(I)(2,5-dimethylphenyl)diphenylphosphane 
• 1430214-85-9 (2,5-dimethylphenyl)diphenylphosphine oxide 

Relevant academic research and scientific papers

Preparation method of aryl diphenyl phosphine derivative

The invention belongs to the technical field of preparation of organic compounds, and discloses a preparation method of an aryl diphenyl phosphine derivative. The method comprises the following stepsof adding a bromobenzene derivative, diphenylphosphine and KOH into a solvent, and reacting at 100-130 DEG C under the protection of nitrogen to obtain the aryl diphenylphosphine derivative. KOH is used as a catalyst, and a noble metal catalyst is not needed, so that the cost is reduced, and the method is green and environment-friendly; and the method is simple to operate, high in safety, high inyield and suitable for large-scale production.

Efficient potassium hydroxide promoted P-arylation of aryl halides with diphenylphosphine

A simple synthetic method of triarylphosphine compounds by KOH-promoted P-Arylation reaction of aryl halides with diphenylphosphine is presented. Notably, this transformation could smoothly proceed with high yields under transition-metal-free and mild reaction conditions. In addition, this protocol is valuable for industrial application due to the convenient operation and readily accessible aromatic halides. A possible explanation of the reaction mechanism was proposed based on the experimental data.

Preparing method of triarylphosphine compound

The invention belongs to the technical field of medicine and natural compound chemical intermediates and relevant chemistry, and provides a preparing method of a triarylphosphine compound. According to the preparing method, a diphenylphosphine compound and aryl halide serve as raw materials, participation of transition metal catalysts is not needed, and the triarylphosphine compound is constructedin one step under the heating condition. The preparing method has the advantages that according to the reaction, the metal or non-metal catalysts are not needed for catalytic reactions, the triarylphosphine compound is clean and free of pollution, the reaction condition is mild, the operation and aftertreatment are simple, and the substrate compatibility is good.