59325-11-0

Basic information

• Product Name: 1-Piperazinecarboxylicacid,4-methyl-,ethylester(6CI,9CI)
• Synonyms: 1-Piperazinecarboxylicacid,4-methyl-,ethylester(6CI,9CI);ETHYL 4-METHYLPIPERAZINE-1-CARBOXYLATE
• CAS NO: 59325-11-0
• Molecular Formula: C₈H₁₆N₂O₂
• Molecular Weight: 172.22
• Product Categories: PIPERIDINE
• Mol File: 59325-11-0.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 97-98 °C(Press: 8 Torr)
• Appearance: /
• Density: 1.058±0.06 g/cm3(Predicted)
• PKA: 6.91±0.10(Predicted)
• CAS DataBase Reference: 1-Piperazinecarboxylicacid,4-methyl-,ethylester(6CI,9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Piperazinecarboxylicacid,4-methyl-,ethylester(6CI,9CI)(59325-11-0)
• EPA Substance Registry System: 1-Piperazinecarboxylicacid,4-methyl-,ethylester(6CI,9CI)(59325-11-0)

Safety Data

• Hazardous Substances Data: 59325-11-0(Hazardous Substances Data)

Usage

Usage

Intermediate in the production of pharmaceuticals and agrochemicals

Potential use

Corrosion inhibitor

Pre-clinical studies

Exhibits anticonvulsant and analgesic properties

Importance

Has potential applications in medicine and chemical research

Upstream product

• 109-01-3 1-methyl-piperazine 
• 541-41-3 chloroformic acid ethyl ester 
• 120-43-4 4-ethoxycarbonylpiperazine 
• 50-00-0 formaldehyd 

Downstream Products

• 109647-44-1 4-ethoxycarbonyl-1-methyl-1-undecyl-piperazinium; bromide 
• 124114-31-4 4-ethoxycarbonyl-1-methyl-1-tridecyl-piperazinium; bromide 
• 119150-80-0 4-ethoxycarbonyl-1-methyl-1-tetradecyl-piperazinium; bromide 
• 108993-56-2 4-ethoxycarbonyl-1-methyl-1-prop-2-ynyl-piperazinium; bromide 
• 4223-93-2 2-Diaethylaminoaethyl-4-methylpiperazin-1-carboxylat 
• 109-01-3 1-methyl-piperazine 
• 109648-86-4 1-methyl-1-tetradecyl-piperazinium; chloride-hydrochloride 
• 111440-03-0 1-methyl-1-tridecyl-piperazinium; chloride-hydrochloride 
• 104-19-8 N-methyl-N'-(2-dimethylaminoethyl)piperazine 

Relevant articles and documents

Substituted carboxamide analogues as a new class of local anesthetic agents: Synthesis and bio-evaluation

A series of N-(2-oxo-2-(phenylamino) ethyl) substituted-4-carboxamide derivatives were synthesized as local anesthetic agents. The structures of carboxamide derivatives were established on the basis of IR, and1H spectral data. All the compounds were subjected to surface local anesthetic activity assay and infiltration local anesthetic activity assay. Among the tested compounds, N-(2-oxo-2-(p-tolylamino) ethyl) piperidine-1-carboxamide (4h) and N-(2-((4-methoxyphenyl) amino)-2-oxoethyl) piperidine-1-carboxamide (4m) were most promising compounds in terms of surface local anaesthetic and infiltration local anaesthetic activity on rats having considerably lower liver toxicity.

Titanium(IV) Isopropoxide and Sodium Borohydride: A Reagent of Choice for Reductive Amination

The preliminary results on the novel use of titanium(IV) isopropoxide and sodium borohydride in reductive amination reactions are reported.A highly efficient and mild procedure for reductive aminations of formaldehyde with a variety of primary and secondary amines is described.

On the cleavage of tertiary amines with ethyl chloroformate

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