59349-74-5

Upstream product

• 616-75-1 (S)-(+)-2-phenylsuccinic acid 
• 62624-46-8 (S)-(+)-3-phenylpyrrolidine 
• 98-80-6 phenylboronic acid 
• 6837-05-4 (2S)-2-phenylbutane-1,4-diol 
• 164653-83-2 methanesulfonic acid (S)-4-methanesulfonyloxy-3-phenyl-butyl ester 
• 100-46-9 benzylamine 
• 159528-25-3 (S)-di-tert-butyl-2-phenylsuccinate 
• 100-39-0 benzyl bromide 

Downstream Products

• 123724-34-5 (S)-(R*,R*)-N-<<α-methoxy-α-(trifluoromethyl)phenyl>-acetyl>-3-phenylpyrrolidine 
• 62624-46-8 (S)-(+)-3-phenylpyrrolidine 

Relevant academic research and scientific papers

Preparation of chiral 3-arylpyrrolidines via the enantioselective 1,4-addition of arylboronic acids to fumaric esters catalyzed by Rh(I)/chiral diene complexes

A highly efficient rhodium-catalyzed protocol for the preparation of 2-arylsuccinic esters and 3-arylpyrrolidines of high optical purity has been achieved. In the presence of 1 mol % of a chiral diene/Rh(I) catalyst, asymmetric addition of various arylbor

STUDY OF THE ASYMMETRIC INDUCTION OF THE 1,3-DIPOLAR CYCLOADDITION OF CHIRAL AZOMETHINE YLIDES WITH UNACTIVATED DOUBLE BONDS

The asymmetric induction of the 1,3-dipolar cycloaddition reaction between nonstabilized azomethine ylides generated by deprotonation of the corresponding tertiary amine N-oxides (1a-f) with a base and various unactivated olefins (2a-c) or dienes (2d-e) h