594-05-8

Basic information

• Product Name: UREA, [14C]
• Synonyms: [14C]UREA;UREA, [14C];UREA-14C 40-60 MCI PER MMOL
• CAS NO: 594-05-8
• Molecular Formula: CH₄N₂O
• Molecular Weight: 62.07
• Mol File: 594-05-8.mol

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: UREA, [14C](CAS DataBase Reference)
• NIST Chemistry Reference: UREA, [14C](594-05-8)
• EPA Substance Registry System: UREA, [14C](594-05-8)

Safety Data

• Hazard Codes: R,Xn
• Statements: 36/37/38-40
• Safety Statements: 22-26-36
• RIDADR: UN 2910 7
• WGK Germany: 3
• Hazardous Substances Data: 594-05-8(Hazardous Substances Data)

Upstream product

• 1204354-59-5 C₂⁽¹⁴⁾C₂H₆N₄O₃ 
• 67877-97-8 potassium [¹⁴C]cyanate 
• 21420-36-0 [¹⁴C]cyanamide 
• 51-90-1 [14C]carbon dioxide 
• 57-13-6 urea 

Downstream Products

• 67877-97-8 potassium [¹⁴C]cyanate 
• 626-07-3 <2-(14)C>uracil 
• 1278406-07-7 methyl 4-(4-fluorophenyl)-6-isopropyl-2-[⁽¹⁴⁾C]-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate 
• 57-13-6 urea 

Relevant articles and documents

Purine nucleotide catabolism in rat liver. Certain preliminary aspects of uricase reaction

We investigated the mechanism of action of uricase, which oxidizes uric acid to allantoin, in the rat. Allantoin may decompose chemically to urea and hydantoin, containing the carbons in positions 2 and 8 of the purine ring, respectively. These carbons ar

Synthesis of [3-14C]- and [5-14C]-labelled 5-nitro-1,2,4-triazol-3-one (NTO) and study of its chemical decomposition

The chemical decomposition of NTO 1 and its corresponding amine ATO 2 was investigated. To make easier the identification of the decomposition products, we synthesized 14C-labelled NTO and ATO. Our results confirmed the high stability of the NTO triazolone ring. Its scission can be achieved partially by sulfuric acid under intensive heat and pressure. The triazolone ring of ATO was cleaved in alkaline solution. Carbon dioxide is evolved leaving a polar compound assumed to be aminoguanidine. The deamination of ATO was achieved by nitrosation. In dilute HCl (0.15 N), 2 equivalents of NO2- led to the triazolone 4, through a radical de-diazotation of the diazo intermediate. With 3 to 10 equivalents of NO2-, the nitrosation leads exclusively to the azide 6.

In vivo and in vitro studies of urea formation from a ω-1 hydroxybarbiturate: Proxibarbal

Proxibarbal-ω-1 hydroxybarbiturate undergoes more easily than non hydroxylated barbiturates a ring opening and yields urea. In vivo and in vitro studies of this degradation were performed, under biomimetic conditions, and the mechanism is elucidated.