626-07-3 Usage
Uses
Used in Scientific Research:
URACIL, [2-14C] is used as a tracer compound for studying the incorporation of uracil into RNA molecules and its metabolic pathways in living organisms.
Used in Molecular Biology:
URACIL, [2-14C] is used as a research tool for investigating RNA synthesis, degradation, and turnover processes, as well as the role of uracil in cellular functions and metabolism.
Used in Radioactive Tracing Studies:
URACIL, [2-14C] is used as a radioactive tracer to track the pathway and fate of uracil in biological systems, providing insights into its behavior and interactions within living organisms.
Used in Environmental and Health Risk Assessment:
URACIL, [2-14C] can be used to assess the environmental and health risks associated with the handling and disposal of radioactive chemicals, ensuring proper safety measures are in place to prevent potential hazards.
Check Digit Verification of cas no
The CAS Registry Mumber 626-07-3 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,2 and 6 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 626-07:
(5*6)+(4*2)+(3*6)+(2*0)+(1*7)=63
63 % 10 = 3
So 626-07-3 is a valid CAS Registry Number.
626-07-3Relevant academic research and scientific papers
PROCESSES AND INTERMEDIATES FOR PRODUCING AZAINDOLES
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Paragraph 0430-0431, (2013/03/26)
The present invention relates to processes and intermediates for the preparation of compounds useful as inhibitors of Janus kinases (JAK).
Zebularine metabolism by aldehyde oxidase in hepatic cytosol from humans, monkeys, dogs, rats, and mice: Influence of sex and inhibitors
Klecker, Raymond W.,Cysyk, Richard L.,Collins, Jerry M.
, p. 62 - 66 (2007/10/03)
To aid in the clinical evaluation of zebularine, a potential oral antitumor agent, we initiated studies on the metabolism of zebularine in liver cytosol from humans and other mammals. Metabolism by aldehyde oxidase (AO, EC 1.2.3.1) was the major catabolic route, yielding uridine as the primary metabolite, which was metabolized further to uracil by uridine phosphorylase. The inhibition of zebularine metabolism was studied using raloxifene, a known potent inhibitor of AO, and 5-benzylacyclouridine (BAU), a previously undescribed inhibitor of AO. The Michaelis-Menten kinetics of aldehyde oxidase and its inhibition by raloxifene and BAU were highly variable between species.
