59401-08-0

Upstream product

• 94-99-5 2,4-Dichlorobenzyl chloride 
• 59363-09-6 2,4-dichloro-α-(chloromethyl)benzenepropanol 
• 104-15-4 toluene-4-sulfonic acid 
• 2631-72-3 2,4-dichlorophenacyl bromide 
• 59363-18-7 4-(2,4-Dichloro-phenyl)-butane-1,2-diol 

Relevant academic research and scientific papers

Antimycotic Imidazoles. 5. Synthesis and Antimycotic Properties of 1-methyl>-1H-imidazoles

The synthesis of 1-methyl>-1H-imidazoles is described starting with phenylacetyl bromides or 1-(phenylacetyl)imidazoles.The compounds were generally obtained as cis/trans mixtures and found to be active in vitro against dermatophytes, yeasts, other fungi, and Gram-positive bacteria.Some also showed good activity against Candida albicans in vivo.

2-Aryl-2-halomethyl-4-alkenyl-1,3-dioxolanes

Novel compounds denoted as 2-aryl-2-halomethyl-4-alkenyl-1,3-dioxolanes used as intermediates in making 1-(2-Ar-4-R-1,3-dioxolan-2-ylmethyl)imidazoles, useful as antifungal and antibacterial agents.

1,3-Dioxolan-2-ylmethylimidazoles

Novel 1-(2-Ar1 -4-Ar2 -1,3-dioxolan-2-ylmethyl)imidazoles, 1-[2-Ar1 -4-(Ar2 -oxymethyl)-1,3-dioxolan-2-ylmethyl]imidazoles, 1-[2-Ar1 -4-(Ar2 -thiomethyl)-1,3-dioxolan-2-ylmethyl]imidazoles,