59433-90-8

Usage

Structure

Bicyclic compound with a naphthalene ring and an azetidinone ring
Potential biological and pharmacological activities
Potential use in drug discovery and development
Potential use in studies exploring interactions with biological systems
Various industrial applications
Need for further research into properties and potential applications

Upstream product

• 1189-71-5 isocyanate de chlorosulfonyle 
• 447-53-0 1,2-Dihydronaphthalene 

Downstream Products

• 401843-49-0 {2-[2-(4-tert-butylcarbamoyl-4-cyclohexyl-piperidin-1-yl)-1-(4-chloro-benzyl)-2-oxo-ethylcarbamoyl]-1,2,3,4-tetrahydro-naphthalen-1-yl}-carbamic acid tert-butyl ester 

Relevant academic research and scientific papers

1-Amino-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid as a Tic mimetic: Application in the synthesis of potent human melanocortin-4 receptor selective agonists

The discovery of 1-amino-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid analogs as potent human melanocortin-4 selective agonists is described.

SUBSTITUTED PIPERIDINES AS MELANOCORTIN RECEPTOR AGONISTS

Certain novel 4-substituted piperidine compounds are agonists of the human melanocortin receptor(s) and, in particular, are selective agonists of the human melanocortin-4 receptor (MC-4R). They are therefore useful for the treatment, control, or prevention of diseases and disorders responsive to the activation of MC-4R, such as obesity, diabetes, sexual dysfunction, including erectile dysfunction and female sexual dysfunction.