59469-08-8 Usage
Description
8-chloro-6-(2-fluoro-phenyl)-1-methyl-3a,4,5,6-tetrahydro-3H-benzo[f]imidazo[5,1-a][1,4]diazepine is a chemical compound with a complex molecular structure, characterized by its potential pharmaceutical applications and its role as an impurity in the synthesis of certain medications.
Uses
Used in Pharmaceutical Industry:
8-chloro-6-(2-fluoro-phenyl)-1-methyl-3a,4,5,6-tetrahydro-3H-benzo[f]imidazo[5,1-a][1,4]diazepine is used as an impurity in the synthesis of Midazolam (M343000), a drug known for its anticonvulsant, sedative, and hypnotic properties. It is particularly effective in the treatment of acute seizures and is valued for its ability to provide relief from these conditions.
As an impurity in the production of Midazolam, 8-chloro-6-(2-fluoro-phenyl)-1-methyl-3a,4,5,6-tetrahydro-3H-benzo[f]imidazo[5,1-a][1,4]diazepine plays a crucial role in ensuring the quality and safety of the final medication. By monitoring and controlling the presence of this impurity, pharmaceutical manufacturers can maintain the efficacy and reliability of Midazolam as a treatment option for various medical conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 59469-08-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,9,4,6 and 9 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 59469-08:
(7*5)+(6*9)+(5*4)+(4*6)+(3*9)+(2*0)+(1*8)=168
168 % 10 = 8
So 59469-08-8 is a valid CAS Registry Number.
59469-08-8Relevant articles and documents
Imidazodiazepines and processes therefor
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, (2008/06/13)
Novel Imidazobenzodiazepines and their analogs are useful as anticonvulsants, muscle relaxant, anxiolytic and sedative agents. Preferred compounds of this class belong to the imidazo[1,5-a][1,4]diazepine series which may have a very wide variety of organic substituents. An especially preferred genus included within the purview of the invention encompasses a compound of the formula STR1 wherein R1 is hydrogen and lower alkyl preferably methyl; R3 and R5 are hydrogen; R4 is hydrogen, nitro and halogen, most preferably, chlorine, and in a most preferred embodiment when positioned on the fused benzo portion of the imidazobenzodiazepine is in the 8-position thereof, R6 is phenyl or halo, nitro, or lower alkyl-substituted phenyl, preferably, halo, with fluorine being the preferred halogen, the substituted fluoro being positioned in the 2-position of the phenyl moiety and R2 is hydrogen and lower alkyl.