59469-54-4

Basic information

• Product Name: di-morpholin-4-yl-phosphinic acid 7-nitro-5-phenyl-3H-benzo[e][1,4]diazepin-2-yl ester
• CAS NO: 59469-54-4
• Molecular Weight: 499.463
• Mol File: 59469-54-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: di-morpholin-4-yl-phosphinic acid 7-nitro-5-phenyl-3H-benzo[e][1,4]diazepin-2-yl ester(CAS DataBase Reference)
• NIST Chemistry Reference: di-morpholin-4-yl-phosphinic acid 7-nitro-5-phenyl-3H-benzo[e][1,4]diazepin-2-yl ester(59469-54-4)
• EPA Substance Registry System: di-morpholin-4-yl-phosphinic acid 7-nitro-5-phenyl-3H-benzo[e][1,4]diazepin-2-yl ester(59469-54-4)

Safety Data

• Hazardous Substances Data: 59469-54-4(Hazardous Substances Data)

Upstream product

• 7264-90-6 di-morpholin-4-yl-phosphinic acid chloride 
• 146-22-5 nitrazepam 

Relevant articles and documents

Imidazodiazepines and processes therefor

Novel Imidazobenzodiazepines and their analogs are useful as anticonvulsants, muscle relaxant, anxiolytic and sedative agents. Preferred compounds of this class belong to the imidazo[1,5-a][1,4]diazepine series which may have a very wide variety of organic substituents. An especially preferred genus included within the purview of the invention encompasses a compound of the formula STR1 wherein R1 is hydrogen and lower alkyl preferably methyl; R3 and R5 are hydrogen; R4 is hydrogen, nitro and halogen, most preferably, chlorine, and in a most preferred embodiment when positioned on the fused benzo portion of the imidazobenzodiazepine is in the 8-position thereof, R6 is phenyl or halo, nitro, or lower alkyl-substituted phenyl, preferably, halo, with fluorine being the preferred halogen, the substituted fluoro being positioned in the 2-position of the phenyl moiety and R2 is hydrogen and lower alkyl.