59472-05-8

Upstream product

• 10422-35-2 1-bromo-2-methyl-butane 
• 62-53-3 aniline 
• 6668-42-4 2-methyl-1-phenylbutan-1-one oxime 
• 96-17-3 2-Methylbutyraldehyde 
• 98-95-3 nitrobenzene 
• 137-32-6 (+/-)-2-methyl-1-butanol 
• 589-09-3 N-allyl-N-phenylamine 
• 557-18-6 diethylmagnesium 
• 54394-78-4 2-methylbutanoic acid anilide 

Relevant academic research and scientific papers

Solvent-free one-pot reduction of imines generated in situ from aldehydes and aniline by tributyltin hydride on silica gel

Imines generated in situ from aldehydes and aniline can be reduced using tributyltin hydride on silica gel under solvent-free conditions to provide the corresponding amines in good yields.

Simple reversible fixation of a magnetic catalyst in a continuous flow system: Ultrafast reduction of nitroarenes and subsequent reductive amination using ammonia borane

Continuous reductive amination of aldehydes with nitroarenes over a Pd-Pt-Fe3O4 catalyst was performed. We used NH3BH3 as not only a hydrogen source for nitro reduction, but also a reductant for imine reduction. Secondary aromatic amines were obtained in the continuous flow reaction in good to excellent yields.

Method for synthesizing N-alkyl arylamine

The invention discloses a method for synthesizing N-alkyl arylamine. The method comprises the steps of adding amine, alcohol, a metal iridium catalyst, alkali to a reaction vessel for reflux reaction,cooling to room temperature after reaction, spin-drying a solvent and then conducting separation on columns to obtain a target compound. According to the method for synthesizing the N-alkyl arylamine, a series of N-benzylaniline derivatives are prepared by using transition metal iridium as the catalyst, weak base is used, by-product is water, and a product has relatively good yield, and has certain applicable value.

Use of a Cyclometalated Iridium(III) Complex Containing a N∧C∧N-Coordinating Terdentate Ligand as a Catalyst for the α-Alkylation of Ketones and N-Alkylation of Amines with Alcohols

A cyclometalated iridium(III) complex containing a N∧C∧N-coordinating terdentate ligand [Ir(dpyx-N,C,N)Cl(μ-Cl)]2 was found to be a general and highly effective catalyst for the α-alkylation of ketones and N-alkylation of amines with alcohols. In the presence of catalyst (1 mol % Ir) and base (0.2-0.5 equiv), a variety of desirable products were obtained in good yields under an air atmosphere. Notably, this research exhibited the new potential of Ir(III) complexes bearing non-Cp? ligand and will facilitate the progress of the hydrogen autotransfer process.

Chiral organometallic compounds

A chiral, organometallic compound which, at a molecular level, has no C2 symmetry and comprises a carbon to carbon bond joining a chiral carbon atom to a carbon atom of a cyclopentadiene ring that is non-symmetrically substituted. Examples of such compounds include compounds of formula (I): STR1 wherein X1 and X2 are, independently, groups which are removable during a chemical reaction; M is titanium, zirconium or hafnium; and R1-8,11 are as specified in the description.