5948-68-5

Basic information

• Product Name: 1,2,3,4-Tetrahydro-4-(2-hydroxyphenyl)-6-Methyl-2-oxo-5-pyriMidinecarboxylic acid ethyl ester
• Synonyms: 1,2,3,4-Tetrahydro-4-(2-hydroxyphenyl)-6-Methyl-2-oxo-5-pyriMidinecarboxylic acid ethyl ester
• CAS NO: 5948-68-5
• Molecular Formula: C₁₄H₁₆N₂O₄
• Molecular Weight: 276.28784
• Mol File: 5948-68-5.mol
• Article Data: 107

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1,2,3,4-Tetrahydro-4-(2-hydroxyphenyl)-6-Methyl-2-oxo-5-pyriMidinecarboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2,3,4-Tetrahydro-4-(2-hydroxyphenyl)-6-Methyl-2-oxo-5-pyriMidinecarboxylic acid ethyl ester(5948-68-5)
• EPA Substance Registry System: 1,2,3,4-Tetrahydro-4-(2-hydroxyphenyl)-6-Methyl-2-oxo-5-pyriMidinecarboxylic acid ethyl ester(5948-68-5)

Safety Data

• Hazardous Substances Data: 5948-68-5(Hazardous Substances Data)

Usage

General Description

1,2,3,4-Tetrahydro-4-(2-hydroxyphenyl)-6-methyl-2-oxo-5-pyrimidinecarboxylic acid ethyl ester is a chemical compound with a complex structure. It contains a tetrahydro-pyrimidine ring with a 2-hydroxyphenyl and a methyl group attached, as well as an ethyl ester functional group. 1,2,3,4-Tetrahydro-4-(2-hydroxyphenyl)-6-Methyl-2-oxo-5-pyriMidinecarboxylic acid ethyl ester is a derivative of pyrimidine and is often used in the synthesis of pharmaceuticals or in medicinal chemistry research. Its specific properties and potential uses would need to be further investigated through testing and analysis in a laboratory setting.

Upstream product

• 141-97-9 ethyl acetoacetate 
• 90-02-8 salicylaldehyde 
• 57-13-6 urea 
• 89-95-2 2-methyl-benzyl alcohol 
• 4433-85-6 2-ethyl-3-oxobutanoic acid 
• 90-01-7 salicylic alcohol 

Downstream Products

• 1264939-38-9 C₁₂H₁₄N₄O₃ 
• 1254120-60-9 C₁₅H₁₆N₂O₅ 
• 1254120-71-2 C₂₁H₂₀N₂O₅ 
• 1190370-76-3 C₃₂H₂₆N₄O₈ 
• 1190370-73-0 C₃₂H₃₂N₆O₄ 
• 1190370-75-2 C₂₈H₂₆N₈O₄ 
• 1190370-72-9 ethyl 1,3-bis-(benzimidazol-1-yl-methyl)-4-(2-hydroxy-phenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate 
• 1190370-77-4 C₂₄H₃₄N₄O₆ 
• 90-02-8 salicylaldehyde 

Relevant articles and documents

Tungsten-substituted molybdophosphoric acid impregnated with kaolin: effective catalysts for the synthesis of 3,4-dihydropyrimidin-2(1: H)-ones v i a biginelli reaction

A series of highly reusable heterogeneous catalysts (10-25 wt% PMo7W5/kaolin), consisting of tungsten-substituted molybdophosphoric acid, H3PMo7W5O40·24H2O (PMo7W5) impregnated with acid treated kaolin clay was synthesized by the wetness impregnation meth

CoFe2O4?SiO2-NH2-CoII NPs: An effective magnetically recoverable catalyst for Biginelli reaction

Biginelli reaction entails acid-catalyzed one-pot synthesis of 3,4-dihydropyrimidin-2(1H)-ones (DHPMs) with simply-accessible initial substances, specifically, aldehyde, urea, and active methylene compound. DHPMs have stimulated a resurgence of attention in the previous two decades because of their broad-ranging pharmacological actions and the existence of varied all-natural products. Currently, green methods to asymmetric Biginelli reaction have been researched for anti-inflammatory DHPMs. In materials chemistry, DHPMs are increasingly decision applications in the creation of materials like polymers, adhesives, fabric dyes, etc. In light of the simplicity by which the Biginelli reaction is conducted, numerous interesting prospects expect its exploitation in variety fields. CoFe2O4?SiO2-NH2-CoII is herein turned out to be an effective catalyst at a three-component Biginelli reaction. The yield of the corresponding DHPMs was rather large (20 cases; average 92 percent). Finally, we herein suggest a procedure that shows lots of advantages and benefits such as the whole lack of solvents, mild reaction conditions, comparatively short reaction times. Also, CoFe2O4?SiO2-NH2-CoII NPs catalyst has been readily recovered from the reaction combination and reused, without the decrease of catalytic action.

Natural dolomitic limestone-catalyzed synthesis of benzimidazoles, dihydropyrimidinones, and highly substituted pyridines under ultrasound irradiation

Natural dolomitic limestone (NDL) is employed as a heterogeneous green catalyst for the synthesis of medicinally valuable benzimidazoles, dihydropyrimidinones, and highly functionalized pyridines via C–N, C–C, and C–S bond formations in a mixture of ethan