59481-76-4Relevant academic research and scientific papers
Synthesis of an enkephalin analogue containing an α,α- disubstituted heterocyclic aminophosphonic acid
Rabasso, Nicolas,Fadel, Antoine
, p. 1811 - 1819 (2011/10/08)
Synthesis of a phosphonopentapeptide enkephalin analogue was achieved from heterocyclic aminophosphonates via the coupling of Boc-Tyr-Gly-Gly-OH with phosphonodipeptide. The latter was formed by coupling Boc-Phe-OH with N-terminal α,α-disubstituted hetero
Facile Synthesis of N-Protected Peptide Fragments using Polymer-Bound 1-Hydroxybenzotriazole as an Active Ester
Chen, Shui-Tein,Chang, Chung-Ho,Wang, Kung-Tsung
, p. 1967 - 1975 (2007/10/02)
Using polystyrene-bound 1-hydroxybenzotriazole as an active ester and an amino acid or peptide, temporarily C-terminal-protected by a phase-transfer reagent, as a nucleophile, C-terminal-free peptide fragments can be synthesized with very high yield and p
Enkephalin analogs and a process for the preparation thereof
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, (2008/06/13)
The invention relates to new enkephalin analogues of the general formula (I), wherein Tyr, Gly and Phe represent L-tyrosyl, glycyl and L-phenylalanyl residue, respectively, X is glycyl residue or a D-α-aminocarboxylic acid residue with a lower alkyl, lowe
4-Substituted enkephalin derivatives
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, (2008/06/13)
Analogs of methionine 5 -enkephalin and leucine 5 -enkephalin wherein the L-phenylalanyl residue in position 4 has been substituted by various other amino acid residues are disclosed herein. These analogs exhibit agonist activity at opiate receptor sites
