5949-65-5Relevant academic research and scientific papers
Cu-catalyzed cascade reaction of isoxazoles with diaryliodonium salts for the synthesis of acridines
Li, Jian,Lu, Xuechen,Xu, Qiuneng,Yan, Shenghu,Zhu, Shangrong
, p. 944 - 950 (2020/12/23)
A straightforward and efficient synthesis of acridine derivatives via a copper-catalyzed cascade reaction among isoxazoles and diaryliodonium salts is achieved. Various mono-, multi-substituted and 9-substituted acridine derivatives could be obtained in moderate to good yields. The process has gone through tandem double arylation and Friedel-Crafts reactions.
