59523-07-8Relevant academic research and scientific papers
Functionalization of unprotected uracil derivatives using the halogen - Magnesium exchange
Kopp, Felix,Knoechel, Paul
, p. 1639 - 1641 (2008/02/02)
The reaction of commercially available 5-iodouracil with 2 equiv of MeMgCl in the presence of LiCl, followed by the addition of i-PrMgCl-LiCl, provides the corresponding trimagnesiated species, which reacts with various electrophiles to give selectively 5
Preparation of allyl-, alkenyl- and of functionalized arylmanganese reagents by oxidative insertion of manganese-graphite into organic halides
Fuerstner, Alois,Brunner, Heiko
, p. 7009 - 7012 (2007/10/03)
Reduction of MnBr2·nLiBr (n = 1,2) with 2 C8K in THF affords highly active Mn-graphite, which readily insert into allyl-, alkenyl-, (substituted) aryl- and heteroaryl halides. The functionalized organomanganese compounds thus obtained may be efficiently trapped with different electrophiles such as aldehydes, anhydrides and acid chlorides, or can be cross-coupled with alkenyl halides in the presence of catalytic amounts of Fe(acac)3.
Synthesis of silyl and stannyl pyrimidines
Parkanyi, Cyril,Cho, Nam Sook,Yoo, Geon Seek
, p. 1 - 8 (2007/10/02)
2,4-dimethoxy- and 2,4-dibenzyloxy-5-lithiopyrimidines, obtained from the corresponding substituted 5-bromopyrimidines, react with trimethylsilyl chloride or trimethylstannyl chloride to give the appropriate 5-trimethylsilyl or trimethylstannyl derivative
