59549-86-9

Upstream product

• 109-72-8 n-butyllithium 
• 18666-55-2 (1,2-epoxyethyl)triphenylsilane 
• 693-02-7 hex-1-yne 
• 789-25-3 HSiPh₃ 
• 18666-68-7 vinyltriphenylsilane 
• 75-77-4 chloro-trimethyl-silane 

Relevant academic research and scientific papers

Tri(t-butyl)phosphine-assisted selective hydrosilylation of terminal alkynes

A highly efficient and regio-/stereoselective method of hydrosilylating terminal alkynes was developed using Pt(DVDS)-tri(t-butyl)phosphine catalyst system at room temperature. Trans-products or alpha-products were obtained almost exclusively depending on

Generation and reactions of α-silyloxiranyllithium in a mieroreactor

α-Triphenylsilyloxiranyllithium was effectively generated by the reaction of epoxyethyltriphenylsilane with n-BuLi in a microflow reactor at 0°C, though it is well known that an over reaction cannot be avoided even at lower temperatures in a conventional

Gold-film-catalysed hydrosilylation of alkynes by microwave-assisted, continuous-flow organic synthesis (MACOS)

Thin gold films on the surface of glass capillaries have proven to be highly active catalysts for the rapid hydrosilylation of alkynes that are flowed through the reactor while being heated by microwave irradiation. The films are able to be reused at least five times with no loss of activity and with no detectable levels of gold showing up in the hydrosilylated products.

Novel immobilized hydrosilylation catalysts based on rhodium 1,3-bis(2,4,6-trimethylphenyl)-3,4,5,6-tetrahydropyrimidin-2-ylidenes

The reactivity of a well defined Rh (I) complex, i.e. Rh(CF 3COO)(NHC)(COD) (1, NHC = 1,3-bis(2,4,6-trimethylphenyl)-3,4,5,6- tetrahydropyrimidin-2-ylidene, COD = η4-cycloocta-1,5-diene) in the hydrosilylation of 1-alkenes, alkynes,

Photoactivated hydrosilylation reaction of alkynes

The photoactivated (350 nm) hydrosilylation of alkynes by silanes catalyzed by platinum(II) bis(acetylacetonato) has been studied. Platinum(II) bis(acetylacetonato) is an efficient catalyst. High yields of adducts ( > 98% for terminal alkynes) can be obta

Organosilicon compounds with functional groups proximate to silicon. XVII. Synthetic and mechanistic aspects of the lithiation of α,β-epoxyalkylsilanes and related α-heterosubstituted epoxides

A series of α-heterosubstituted epoxides, , has been found to undergo lithiation in the temperature range of -75 to -115 deg C at the C-H bond of the epoxide.The substituent Z could be Me3Si, Ph3Si, n-Bu3Sn, Ph3Sn, PhSO2, (OEt)2PO and Ph; the groups R and R' were H, Ph and n-C6H13; and the lithiating reagents were n-butyllithium, t-butyllithium and lithium diisopropylamide in donor media of THF or TMEDA.The lithiation occurs with retention of configuration and the resulting lithio-epoxide is unstable above 0 deg C, decomposing in a carbenoid manner.The lithiation is facile except for compounds where Z and R (an alkyl or aryl) are cis-oriented; where Z = R3Sn, lithiation occurs by tin-lithium, rather than hydrogen-lithium, exchange.The lithio-epoxides thereby generated can be quenched with various reagents to yield epoxides where the epoxide H has been replaced by D, Me3Sn, R, RCO and COOH.The utility of this procedure in organic synthesis is emphasized.Finally, the possible explanations for the acidity of such α-heterosubstituted epoxides and for the relative stability of the derived lithio-epoxides are considered and assessed.