595597-01-6

Usage

Uses

Used in Pharmaceutical Industry:
Tert-Butyl N-(1,1-dioxothian-4-yl)carbaMate is used as a pharmaceutical intermediate for the synthesis of various drugs. Its reversible enzyme inhibition properties make it a valuable component in the development of new medications.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, Tert-Butyl N-(1,1-dioxothian-4-yl)carbaMate is employed as a research compound to study enzyme inhibition mechanisms and explore its potential applications in drug discovery.
Used in Agrochemical Production:
Tert-Butyl N-(1,1-dioxothian-4-yl)carbaMate is used as a key component in the production of agrochemicals, contributing to the development of effective and environmentally friendly pesticides and herbicides.
Used in Dye Synthesis:
In the dye industry, Tert-Butyl N-(1,1-dioxothian-4-yl)carbaMate is utilized as a building block for the synthesis of various dyes, offering a wide range of color options and properties for different applications.
Used in Organic Compound Synthesis:
Tert-Butyl N-(1,1-dioxothian-4-yl)carbaMate is used as a versatile building block in the synthesis of various organic compounds, enabling the development of new materials with diverse applications in industries such as pharmaceuticals, agrochemicals, and dyes.

Upstream product

• 21926-00-1 4-tetrahydrothiopyranylamine 
• 24424-99-5 di-tert-butyl dicarbonate 
• 1072-72-6 Tetrahydrothiopyran-4-one 
• 6309-59-7 tetrahydro-4H-thiopyran-4-one oxime 

Downstream Products

• 943434-47-7 N-(1,1-dioxidotetrahydro-2H-thiopyran-4-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonamide 
• 1187448-70-9 4-(5-chloro-2-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)-N-(1,1-dioxotetrahydro-2H-thiopyran-4-yl)benzenesulfonamide 
• 1187448-48-1 4-[2-(1,1-dimethylethyl)-5-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl]-N-(1,1-dioxotetrahydro-2H-thiopyran-4-yl)benzenesulfonamide 
• 1187448-58-3 4-(2-cyclopropyl-5-fluoro-1H-pyrrolo[2,3-b]pyridin-4-yl)-N-(1,1-dioxidotetrahydro-2H-thiopyran-4-yl)benzenesulfonamide 
• 1187448-54-9 4-(5-chloro-2-cyclopropyl-1H-pyrrolo[2,3-b]pyridin-4-yl)-N-(1,1-dioxotetrahydro-2H-thiopyran-4-yl)benzenesulfonamide 
• 1089669-32-8 N-(1,1-dioxidotetrahydro-2H-thiopyran-4-yl)-5-[2-methyl-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-4-yl]-2-thiophenesulfonamide 
• 116529-31-8 1,1-dioxohexahydro-1λ6-thiopyran-4-ylamine hydrochloride 
• 210240-20-3 4-aminotetrahydro-2H-thiopyran-1,1-dioxide 

Relevant academic research and scientific papers

Discovery, synthesis, and biological evaluation of thiazoloquin(az)olin(on)es as potent CD38 inhibitors

A series of thiazoloquin(az)olinones were synthesized and found to have potent inhibitory activity against CD38. Several of these compounds were also shown to have good pharmacokinetic properties and demonstrated the ability to elevate NAD levels in plasm

1-(DIHYDRONAPHTHALENYL)PYRIDONES AS MELANIN-CONCENTRATING HORMONE RECEPTOR 1 ANTAGONISTS

Provided are 1-(dihydronaphthalenyl)pyridones which are antagonists at the melanin-concentrating hormone receptor 1 (MCHR1), pharmaceutical compositions containing them, processes for their preparation, and their use in therapy for the treatment of obesity and diabetes.

HETEROCYCLIC COMPOUND

The present invention provides to a compound having melanin-concentrating hormone receptor antagonistic action and low toxicity, and useful as a agent for the prophylaxis or treatment of obesity and the like. The present invention relates to a compound re

NOVEL COMPOUNDS

The invention is directed to certain novel compounds. Specifically, the invention is directed to compounds according to formula (I) and salts thereof. The compounds of the invention are inhibitors of kinase activity, in particular IKK2 activity.

Kinase inhibitor compounds

The invention relates to compounds, compositions comprising the compounds, and methods of using the compounds and compound compositions. The compounds, compositions, and methods described herein can be used for the therapeutic modulation of kinase-mediated processes, and treatment of disease and disease symptoms, particularly those mediated by certain kinase enzymes.

NOVEL COMPOUNDS

The invention is directed to certain novel compounds. Specifically, the invention is directed to compounds according to formula (I) and salts thereof. The compounds of the invention are inhibitors of kinase activity, in particular IKK2 activity.

KINASE INHIBITOR COMPOUNDS

The invention relates to compounds, compositions comprising the compounds, and methods of using the compounds and compound compositions. The compounds, compositions, and methods described herein can be used for the therapeutic modulation of kinase-mediated processes, and treatment of disease and disease symptoms, particularly those mediated by certain kinase enzymes.

AZOLE COMPOUNDS

The present invention provides a compound represented by the formula (I) wherein R1 is a hydrogen atom, a halogen atom, an optionally substituted hydrocarbon group, an optionally substituted heterocyclic group, an optionally substituted hydroxy group, an optionally substituted thiol group or an optionally substituted amino group, A is an optionally substituted cyclic amino group or -NR2-W-D wherein R2 is a hydrogen atom or an alkyl group, W is a bond or a divalent acyclic hydrocarbon group, and D is an optionally substituted cyclic group, an optionally substituted amino group or an optionally substituted acyl group, B is an optionally substituted hydrocarbon group or an optionally substituted heterocyclic group, X is an oxygen atom, a sulfur atom or an optionally substituted nitrogen atom, and Y is a bond or a divalent acyclic hydrocarbon group, or a salt thereof, which is useful for the prophylaxis or treatment of diabetic neuropathy and the like.