59569-84-5

Upstream product

• 98-88-4 benzoyl chloride 
• 54262-83-8 (S)-9-(2,3-dihydroxypropyl)adenine 
• 54262-84-9 (S)-9-(1,2-isopropylidenedioxyprop-3-yl)-adenine 
• 115196-66-2 N³,N⁶-Dibenzoyl-2',3'-O-isopropylidene-9-(S)-(2,3-dihydroxypropyl)adenine 
• 115196-67-3 N⁶-Benzoyl-2',3'-O-isopropylidene-9-(S)-(2,3-dihydroxypropyl)adenine 

Downstream Products

• 115589-72-5 9-(S)-(3-Triphenylmethoxy-2-hydroxypropyl)-N⁶-benzoyladenine 
• 201664-42-8 (S)-6-N-benzoyl-9-(2,3-dibenzoyloxypropyl)adenine 
• 115196-68-4 Chloromethyl-phosphonic acid mono-[(S)-2-(6-benzoylamino-purin-9-yl)-1-hydroxymethyl-ethyl] ester 
• 92999-29-6 (S)-9-(3-hydroxy-2-phosphonylmethoxypropyl)adenine 
• 115196-71-9 Benzoic acid (S)-1-(6-benzoylamino-purin-9-ylmethyl)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxy]-ethyl ester 
• 115196-73-1 [(S)-1-(6-Benzoylamino-purin-9-ylmethyl)-2-trityloxy-ethoxymethyl]-phosphonic acid dimethyl ester 
• 115196-72-0 9-(S)-(2-Benzoyloxy-3-hydroxypropyl)-N⁶-benzoyladenine 
• 115196-70-8 3'-O-Bis(p-methoxyphenyl)phenylmethyl-9-(S)-(2,3-dihydroxypropyl)-N⁶-benzoyladenine 

Relevant academic research and scientific papers

SYNTHESIS OF ISOMERIC AND ENANTIOMERIC O-PHOSPHONYLMETHYL DERIVATIVES OF 9-(2,3-DIHYDROXYPROPYL)ADENINE

Reaction of 9-(S)-(2,3-dihydroxypropyl)adenine (I) with chloromethanephosphonyl chloride (VII) in pyridine or triethyl phosphate, or with chloromethyl(pyridinio)phosphonate (IX) in pyridine, afforded a mixture of 2'-(IV) and 3'-O-chloromethanephosphonate