5959-39-7Relevant academic research and scientific papers
Carboxylic Acid Compounds and Use Thereof
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Page/Page column 77, (2010/11/28)
Provision of a superior URAT1 activity inhibitor effective for the treatment and the like of a pathology involving uric acid, such as hyperuricemia, gouty tophus, acute gouty arthritis, chronic gouty arthritis, gouty kidney, urinary lithiasis, renal dysfunction, coronary heart disease, ischemic cardiac diseases and the like. A URAT1 activity inhibitor containing a compound represented by the following formula [1] or a pharmaceutically acceptable salt thereof, or a solvate thereof as an active ingredient: [image] wherein each symbol is as defined in the specification.
QUINONE DIAZIDE CYCLIZATIONS - A DIRECT ROUTE TO DIHYDROBENZOFURANS
Kraus, G. A.,Nagy, J. O.,DeLano, J.
, p. 2337 - 2340 (2007/10/02)
The reaction of ortho-quinone diazides with electron-rich alkenes produces 2,3-dihydrobenzofurans.The ortho-quinone diazides are formed the ortho-nitrophenols by reduction and diazotization.The reaction of an ortho-quinone diazide with 2,3-dihydrofuran produces a furo-benzofuran ring system.
