59593-12-3

Upstream product

• 129679-81-8 (3S,11aS)-8-[Dimethyl-(1,1,2-trimethyl-propyl)-silanyloxy]-3,7-dimethoxy-1,2,3,11a-tetrahydro-benzo[e]pyrrolo[1,2-a][1,4]diazepin-5-one 
• 67-56-1 methanol 
• 59593-16-7 neothramycin B 
• 129679-78-3 (S)-2-tert-Butoxycarbonylamino-pentane-bis-thioic acid di-S-ethyl ester 
• 129679-77-2 4-[Dimethyl-(1,1,2-trimethyl-propyl)-silanyloxy]-5-methoxy-2-nitro-benzoyl chloride 
• 129679-79-4 (S)-2-{2-Amino-4-[dimethyl-(1,1,2-trimethyl-propyl)-silanyloxy]-5-methoxy-benzoylamino}-pentane-bis-thioic acid di-S-ethyl ester 
• 121-33-5 vanillin 
• 129707-60-4 (S)-2-{4-[Dimethyl-(1,1,2-trimethyl-propyl)-silanyloxy]-5-methoxy-2-nitro-benzoylamino}-pentane-bis-thioic acid di-S-ethyl ester 

Relevant academic research and scientific papers

A ONE STEP SYNTHESIS OF 1,4-BENZODIAZEPINES:SYNTHETIC STUDIES ON NEOTHRAMYCIN

A one step synthesis of 1,4-benzodiazepines from o-haloanilines and amino acids was achieved by use of palladium catalyzed carbonylation, by which application a synthesis of the model compounds (23a and 23b) of Neothramycin (A and B) was described.An efficient chemoselective reduction of the amide was provided.