5961-35-3Relevant academic research and scientific papers
Multi experimental and computational studies for DNA and HSA interaction of new nano-scale ultrasound-assisted synthesized Pd(II) complex as a potent anticancer drug
Dehkhodaei, Monireh,Sahihi, Mehdi,Rudbari, Hadi Amiri,Ariaeefar, Mahnaz,Gharaghani, Sajjad,Azadbakht, Reza,Taheri, Salman,Abbasi Kajani, Abolghasem
, p. 386 - 397 (2018)
As for daily increasing mortality rate in world due to the growth of cancer causing agents, design and synthesis of new compounds with anticancer potential benefits is one of the most important challenges for researchers. In the present work, we synthesiz
Salicylaldimines: Formation via Ring Contraction and Synthesis of Mono- And Heterobimetallic Alkali Metal Heterocubanes
Hanft, Anna,Jürgensen, Malte,Wolz, Laura,Radacki, Krzysztof,Lichtenberg, Crispin
, p. 17678 - 17688 (2020/12/22)
The formation of salicylaldimine derivatives via ring contraction as byproducts in 2-aminotropone syntheses has been investigated. Salicylaldiminate (SAI) complexes of the alkali metals Li-K have been synthesized and transformed into heterobimetallic complexes. Important findings include an unusual double heterocubane structure of the homometallic sodium SAI, an unprecedented ligand-induced E/Z isomerization of the aldimine functional group in the homometallic potassium SAI, and the first example of a structurally authenticated mixed-metal SAI based on s-block central atoms. Rapid equilibria have been shown to play a crucial role in the solution phase chemistry of mixed-metal SAIs. Analytical techniques applied in this work include (heteronuclear) NMR spectroscopy, VT- and DOSY NMR spectroscopy, high-resolution mass spectrometry, single-crystal X-ray diffraction analysis, and DFT calculations.
A new oxovanadium(IV) complex containing an O,N-bidentate Schiff base ligand: Synthesis at ambient temperature, characterization, crystal structure and catalytic performance in selective oxidation of sulfides to sulfones using H2O2 under solvent-free conditions
Menati, Saeid,Rudbari, Hadi Amiri,Khorshidifard, Mahsa,Jalilian, Fariba
, p. 94 - 102 (2015/10/12)
A new bidentate ON Schiff base ligand, HL, was synthesized by simple condensation reaction of isopropylamine and salicylaldehyde. Then by reaction of HL and VO(acac)2 in the ratio of 2:1 at ambient temperature, a new oxovanadium(IV) Schiff base complex, VOL2, was synthesized. The Schiff base ligand and its oxovanadium(IV) complex were characterized by elemental analyses, FT-IR, 1H NMR, 13C NMR and UV-visible spectroscopies. The crystal structure of oxovanadium(IV) complex, VOL2, was also determined by single crystal X-ray analysis. The vanadium center in this structure is coordinated to two bidentate Schiff base ligands with the two nitrogen and two phenolate oxygen atoms in equatorial positions and one oxo oxygen in the axial position to complete the distorted trigonal bipyramidal N2O3 coordination sphere. Catalytic performance of the VOL2 complex was studied in the selective oxidation of thioanisole with the green oxidant 35% aqueous H2O2 under solvent-free conditions and under organic solvents (EtOH, CHCl3, CH2Cl2, DMF, CH3CN, EtOAc) as a model. Due to better catalytic performance of the VOL2 complex under solvent-free conditions, this complex used for the oxidation of the different sulfides to the corresponding sulfones under solvent-free conditions. The use of hydrogen peroxide as oxidant and the absence of solvent makes these reactions interesting from environmental and economic points of view.
Carbon dioxide as a carbonylating agent in the synthesis of 2-oxazolidinones, 2-oxazinones, and cyclic ureas: Scope and limitations
Paz, Jairo,Perez-Balado, Carlos,Iglesias, Beatriz,Munoz, Luis
experimental part, p. 3037 - 3046 (2010/07/15)
Carbon dioxide can be used as a convenient carbonylating agent in the synthesis of 2-oxazolidinones, 2-oxazinones, and cyclic ureas. The transient carbamate anion generated by treating a primary or secondary amine group in basic media can be activated with phosphorylating agents such as Diphenylphosphoryl azide (DPPA) and Diphenyl chlorophosphate (DPPCl) but also with other types of electrophiles such as SOCl2, TsCl, or AcCl. The intramolecular trapping of the activated carbamate by a hydroxyl group leads to the formation of 2-oxazolidinones or 2-oxazinones in good to excellent yields. This methodology was successfully applied to the synthesis of cyclic ureas up to 7-membered rings from the corresponding diamines.
Qualitative analysis of the stability of the oxazine ring of various benzoxazine and pyridooxazine derivatives with proton nuclear magnetic resonance spectroscopy
Moloney,Craik,Iskander
, p. 692 - 697 (2007/10/02)
A series of 3,4-dihydro-1,3-benzoxazine and 3,4-dihydro-1,3-pyridooxazine derivatives was synthesized, and the hydrolysis of the derivatives was studied with proton nuclear magnetic resonance spectroscopy. The oxazine derivatives underwent various degrees of hydrolysis when H2O was added to dimethyl sulfoxide solutions of the compounds. The rates and extents of decomposition of the oxazine ring systems depended on the electronic effects of substituents within the molecules. Examination of the proton nuclear magnetic resonance spectra that were generated during decomposition of the oxazines and trends in stability of the oxazine derivatives suggest the formation of an intermediate in the hydrolysis mechanism.
Synthesis and Insect Growth Regulatory Activity of 1,5-Disubstituted Imidazoles with Non-terpene Chains
Kuwano, Eiichi,Hisano, Tomomi,Eto, Morifusa
, p. 2999 - 3004 (2007/10/02)
1-Isobutyl-5-(4-phenoxyphenyl)imidazole (KK-98), an inhibitor of juvenile hormone (JH) biosynthesis in the cockroach, and related imidazole compounds were evaluated against silkworm, Bombyx mori, for their activity to induce precocious metamorphosis.KK-98
The Electrochemical Synthesis of Neutral Zinc(II) Complexes of Schiff Base Ligands: The Crystal Structure of Biszinc(II)
Sogo, T.,Romero, J.,Sousa, A.,Blas, A. de,Duran, M. L.,Castellano, E. E.
, p. 611 - 615 (2007/10/02)
The electrochemical synthesis and physico-chemical properties of neutral zinc(II) complexes of bidentate Schiff bases derived from salicylaldehydes are presented together with the X-ray structure of biszinc(II).The crystal is monoclinic, a = 21.877(3), b = 8.801(2), c = 12.027(5) Angstroem, β = 96.55(3) deg, space group C2/c.The complex is a monomer, and the zinc atom is tetrahedrally coordinated. - Keywords: X-Ray, Zinc, Schiff Bases, Electrochemical Synthesis
X-Ray Structures of Several Bis(N-alkylsalicylaldiminato)zinc(II) Complexes
Dreher, Michael,Elias, Horst,Paulus, Helmut
, p. 707 - 710 (2007/10/02)
X-Ray structures of five bis(N-R-salicylaldiminato)zinc(II) complexes with R = ethyl, n-propyl, i-propyl, n-butyl and 4-thia-n-hexyl were determined.The N2O2 coordination geometry is in all cases quasi-tetrahedral with the dihedral angle between the plane
Syntheses d'aminoalcools-1,3 ou d'aminophenols-1,3 par reduction d'enaminones ou d'iminophenols par les hydrures metalliques. Etude structurale par infrarouge et RMN des aminoalcools-1,3 bisecondaires diastereomeres
Maroni, Pierre,Cazaux, Louis,Tisnes, Pierre,Zambeti,Marianthie
, p. 179 - 186 (2007/10/02)
Enaminones, obtained by reaction of a primary amine with a β-diketone, can take three tautomeric forms: keto-enamine Ia, keto-imine Ib and imino-enol Ic.In general the keto-enamine form Ia is the most stable.Thi
N-Substituted Salicylaldimines Derivatives of Germanium(IV)
Singh, R. V.,Tandon, J. P.
, p. 1391 - 1398 (2007/10/02)
Hexa-coordinated Schiff base complexes of germanium of the general type Ge(OC2H5)2(SB)2 (SB(-) is the anion of the monofunctional bidentate Schiff base, SBH) have been synthesized by the reaction between ethyl-orthogermanate and the Schiff base in benzene
