59629-66-2

Basic information

• Product Name: N-benzyl-N-(2-cyano-ethyl)-acetamide
• Synonyms: N-benzyl-N-(2-cyano-ethyl)-acetamide
• CAS NO: 59629-66-2
• Molecular Weight: 202.256
• Mol File: 59629-66-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-benzyl-N-(2-cyano-ethyl)-acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-benzyl-N-(2-cyano-ethyl)-acetamide(59629-66-2)
• EPA Substance Registry System: N-benzyl-N-(2-cyano-ethyl)-acetamide(59629-66-2)

Safety Data

• Hazardous Substances Data: 59629-66-2(Hazardous Substances Data)

Upstream product

• 706-03-6 3-(benzylamino)propionitrile 
• 75-36-5 acetyl chloride 

Downstream Products

• 140134-63-0 N¹-benzyl-N¹-ethyl-propane-1,3-diamine 
• 14321-27-8 N-ethylbenzylamine 
• 588-46-5 N-(phenylmethyl)acetamide 

Relevant articles and documents

Efficient, asymmetric synthesis of (-)-isooncinotine

Asymmetric synthesis of (-)-isooncinotine, a 22-membered lactam of spermidine alkaloid, starting from resolution of 2-piperidineethanol with (S)-10-camphorsulfonic acid is reported. Michael addition, amidations, and aluminum hydride reduction were applied to form the moiety of spermidine. Retro-Michael addition was observed when β-amido- and β-amino-propionitriles were reduced by LAH. The effects of LAH versus AlH3 were discussed. The synthesis of the skeleton of this macrolide is achieved with ring-closing metathesis of the?diene prepared from acylation of the spermidine.