59636-02-1

Upstream product

• 54887-24-0 2-butylbenzoyl chloride 
• 54887-23-9 2-butylbenzoic acid 

Downstream Products

• 85303-89-5 3-(2-Butyl-phenyl)-5-(3-methoxy-phenyl)-1H-[1,2,4]triazole 
• 85303-88-4 3-(2-Butyl-phenyl)-5-phenyl-1H-[1,2,4]triazole 

Relevant academic research and scientific papers

A New Class of Nonhormonal Pregnancy-Terminating Agents. Synthesis and Contragestational Activity of 3,5-Diaryl-s-triazoles

A series of 3,5-diaryl-s-triazoles were synthesized and evaluated as postimplantation contragestational agents.The introduction of various substituents (e.g., an o-alkyl chain on one phenyl and a m-alkoxy group on the other) was found to increase the potency.Several compounds with very high pregnancy-terminating activity in both hamsters and rats were obtained.One of these, 3-(2-ethylphenyl)-5-(3-methoxyphenyl)-s-triazole, DL 111 (36), was selected for detailed evaluation in various animal species.A synthetic scheme for the preparation of these compounds and preliminary structure-activity relationships are presented.

Microbicidal nitrofuryl compounds

2-[(O-ALKYLAROYLHYDRAZONO)PROPEN-1-YL]-5-NITROFURANS [1] ARE PREPARED BY CONDENSING 3-(5-NITRO-2-FURYL)ACRYLALDEHYDE [2] WITH AN O-ALKYLAROYL HYDRAZIDE [3]. Compounds [1] are bactericides, protozoacides and fungicides and are administrable to animals in therapeutically-acceptable compositions.