54887-24-0

Upstream product

• 57598-33-1 2-(2-methoxyphenyl)-4,4-dimethyl-2-oxazoline 
• 57629-47-7 2-(2-Butylphenyl)-4,4-dimethyl-2-oxazoline 
• 85-44-9 phthalic anhydride 
• 19666-03-6 butyrophenone-o-carboxylic acid 
• 118-90-1 ortho-methylbenzoic acid 
• 54887-23-9 2-butylbenzoic acid 

Downstream Products

• 59059-42-6 2-butylbenzaldehyde 
• 54887-25-1 2-Butyl-benzoic acid 2-diethylamino-ethyl ester 
• 177903-44-5 (2-Butyl-benzoyl)-phosphonic acid dimethyl ester 
• 100256-40-4 2-(n-Butyl)-benzoesaeuremethylester 
• 59636-02-1 o-(n-butyl)benzhydrazide 
• 85303-88-4 3-(2-Butyl-phenyl)-5-phenyl-1H-[1,2,4]triazole 
• 85303-89-5 3-(2-Butyl-phenyl)-5-(3-methoxy-phenyl)-1H-[1,2,4]triazole 
• 34139-46-3 2-n-Butylphenyl-diazomethan 
• 20983-15-7 o-crotyltoluene 
• 111787-49-6 2-butyl-N-phenylbenzamide 

Relevant academic research and scientific papers

N-Heterocyclic-Carbene-Catalyzed C–H Acylation via Radical Relay

A method of N-fluorocarboxamide-directed N-heterocyclic-carbene (NHC)-catalyzed benzylic C–H acylation with aldehydes via the hydrogen atom transfer strategy is disclosed. This transformation involves a sequence of single-electron transfer, 1,5-hydrogen a

Copper-catalyzed aerobic double functionalization of benzylic C(sp3)-H bonds for the synthesis of 3-hydroxyisoindolinones

A copper-catalyzed aerobic 3-hydroxyisoindolinone synthesis was developed via the benzylic double C(sp3)-H functionalization of 2-alkylbenzamides. In this reaction, molecular oxygen was used as both an oxidant for C(sp3)-H functionalization and an oxygen source. Our method can be extended to diverse benzylic C(sp3)-H bonds and shows excellent functional group tolerance. This journal is

Protoberberins from Reissert Compounds VI [1]. Diastereoselective Synthesis and Relative Configuration of 2-Benzoyl-1-cyano-1-(1-phenylalkyl)-1,2-dihydroisoquinolines

The alkylation of Reissert compounds 8 by sec-benzyl bromides 4, 7, and 10 diastereoselectively affords the title compounds 11 and 12. X-Ray structure analysis confirms an opposite configuration of the chiral centers in 11 and 12. The benzyl bromides 4, 7, and 10 are prepared by standard procedures.

The Reactions of Carbene Intermediates from the Reaction of Trialkyl Phosphites with Dialkyl Benzoylphosphonates: Intramolecular Cyclisations of 2-Substituted Dialkyl Benzoylphosphonates

The reaction of dialkyl aroylphosphonates 1 with trialkyl phosphites leads to the formation of carbene intermediates 3 via the anionic intermediates 2.The carbene intermediates 3 (R = 2-Me, 2-Prn, 2-Bun, 2-MeS, 2-EtO and 2-EtS) have

2-(Quinuclidin-3-yl)pyrido[4,3-b]indol-1-ones and isoquinolin-1-ones. Potent conformationally restricted 5-HT3 receptor antagonists

Several series of N-(quinuclidin-3-yl)aryl and heteroaryl-fused pyridones were synthesized and evaluated for 5-HT3 receptor affinity. In the heteroaryl series,2-(quinuclidin-3-yl)tetrahydropyrido[4,3-b]indol-1-one (8a) and the 4,5-alkano-bridge

A New Class of Nonhormonal Pregnancy-Terminating Agents. Synthesis and Contragestational Activity of 3,5-Diaryl-s-triazoles

A series of 3,5-diaryl-s-triazoles were synthesized and evaluated as postimplantation contragestational agents.The introduction of various substituents (e.g., an o-alkyl chain on one phenyl and a m-alkoxy group on the other) was found to increase the potency.Several compounds with very high pregnancy-terminating activity in both hamsters and rats were obtained.One of these, 3-(2-ethylphenyl)-5-(3-methoxyphenyl)-s-triazole, DL 111 (36), was selected for detailed evaluation in various animal species.A synthetic scheme for the preparation of these compounds and preliminary structure-activity relationships are presented.