596807-51-1

Upstream product

• 525-76-8 2-methyl-4-oxo-3,1-benzoxazine 
• 1788-93-8 3-(4-chlorophenyl)-2-methyl-3H-quinazolin-4-one 
• 79-04-9 chloroacetyl chloride 

Downstream Products

• 596807-56-6 3-(4-chloro-phenyl)-2-(3-hydrazino-2-oxo-propyl)-3H-quinazolin-4-one 

Relevant academic research and scientific papers

THIAZOLE AND THIOPHENE ANALOGUES, AND THEIR USE IN TREATING AUTOIMMUNE DISEASES AND CANCERS

Thiazole and thiophene compounds are disclosed having utility in treating inflammatory conditions, immunoinflammatory conditions, autoimmune diseases, and cancers. Methods for the synthesis of these compounds are also disclosed.

Synthesis and anti-inflammatory, analgesic, ulcerogenic and cyclooxygenase activities of novel quinazolinyl-Δ2-pyrazolines

Synthesis of 2-(ω -chloroacetonyl)-3-substituted-phenyl-6-halo/6,8-dihaloquinazolin-4(3H)-ones 6-10, 2-(ω -hydrazinoacetonyl)-3-substituted-phenyl-6-halo/6,8-dihaloquinazolin-4(3H)ones 11-15 and 1′ -[3H-3-substituted-phenyl-4-oxo-6-halo/6,8-dihaloquinazolin-2-acetonyl] -3′-aryl-5′-(2-substituted-indol-3-yl)-Δ 2-pyrazolines 16-30 have been described. All the compounds have been tested in vivo for their anti-inflammatory, analgesic, ulcerogenic activities and acute toxicity.