596807-96-4Relevant academic research and scientific papers
One-pot synthesis of pyridazino[1,4]oxazin-3-ones
Ma, Chen,Cho, Su-Dong,Falck,Shin, Dong-Soo
, p. 1399 - 1405 (2007/10/03)
Pyridazino[1,4]oxazin-3-ones were conveniently prepared in a one-pot condensation of N-substituted 2-chloroacetamides with various 5-chloro-pyridazin-6-ones via rearrangement of a spiro-aminoketal intermediate.
A one-pot synthesis of pyrido[2,3.b][1,4]oxazin-2-ones
Cho, Su-Dong,Park, Yong-Dae,Kim, Jeum-Jong,Lee, Sang-Gyeong,Ma, Chen,Song, Sang-Yong,Joo, Woo-Hong,Falck,Shiro, Motoo,Shin, Dong-Soo,Yoon, Yong-Jin
, p. 7918 - 7920 (2007/10/03)
Pyrido[2,3-b][1,4]oxazin-2-ones are conveniently prepared in excellent yields by a one-pot annulation of N-substituted-2-chloroacetamides with 2-halo-3-hydroxypyridines with use of cesium carbonate in refluxing acetonitrile. The key transformation features a Smiles rearrangement of the initial O-alkylation product and subsequent cyclization.
