596808-09-2

Basic information

• Product Name: Acetamide, 2-[(2-bromo-3-pyridinyl)oxy]-N-[2-(3,4-dimethoxyphenyl)ethyl]-
• CAS NO: 596808-09-2
• Molecular Formula: C17H19BrN2O4
• Molecular Weight: 395.253
• Mol File: 596808-09-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Acetamide, 2-[(2-bromo-3-pyridinyl)oxy]-N-[2-(3,4-dimethoxyphenyl)ethyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetamide, 2-[(2-bromo-3-pyridinyl)oxy]-N-[2-(3,4-dimethoxyphenyl)ethyl]-(596808-09-2)
• EPA Substance Registry System: Acetamide, 2-[(2-bromo-3-pyridinyl)oxy]-N-[2-(3,4-dimethoxyphenyl)ethyl]-(596808-09-2)

Safety Data

• Hazardous Substances Data: 596808-09-2(Hazardous Substances Data)

Upstream product

• 120-20-7 2-(3,4-dimethoxyphenyl)-ethylamine 
• 6602-32-0 2-bromo-pyridin-3-ol 
• 14301-31-6 2-chloro-N-(2-(3,4-dimethoxyphenyl)ethyl)acetamide 

Downstream Products

• 596808-27-4 1-[2-(3,4-dimethoxyphenyl)ethyl]-1H-pyrido[2,3-b][1,4]oxazin-2-one 

Relevant articles and documents

A one-pot synthesis of pyrido[2,3.b][1,4]oxazin-2-ones

Pyrido[2,3-b][1,4]oxazin-2-ones are conveniently prepared in excellent yields by a one-pot annulation of N-substituted-2-chloroacetamides with 2-halo-3-hydroxypyridines with use of cesium carbonate in refluxing acetonitrile. The key transformation features a Smiles rearrangement of the initial O-alkylation product and subsequent cyclization.