59689-64-4

Usage

InChI:InChI=1/C5H9N3S/c1-3(2)4-6-5(9)8-7-4/h3H,1-2H3,(H2,6,7,8,9)

Upstream product

• 79-19-6 thiosemicarbazide 
• 79-30-1 isobutyryl chloride 
• 1147550-11-5 ammonium thiocyanate 
• 3619-17-8 isobutyric acid hydrazide 

Downstream Products

• 99341-58-9 (-)-cis-caran-trans-4-methanol 
• 131566-05-7 cis-caran-cis-4-methanol 
• 1204760-19-9 1-{4-[5-(4-chloro-benzyl)-7-ethoxy-oxazolo[5,4-d]pyrimidin-2-yl]-2,6-dimethyl-phenoxy}-3-(5-isopropyl-4H-[1,2,4]triazol-3-ylsulfanyl)-propan-2-ol 

Relevant academic research and scientific papers

N,N-dialkyl-N′-chlorosulfonyl chloroformamidines in heterocyclic synthesis. VI the preparation of some fused [1,4,2,6]dithiadiazine dioxides

N,N-Dialkyl-N′-chlorosulfonylchloroformamidines 1 were treated with 2-mercaptobenzimidazoles 2 to give [1,4,2,6]dithiadiazino[2,3-a]benzimidazole 1,1-dioxides 3. 3-Mercapto[1,2,4]triazoles 5 afforded [1,2,4]triazolo[2,3-b][1, 4,2,6]dithiadiazine 1,1-dioxides 6 and [1,2,4]triazolo[4,3-b][1,4,2,6] dithiadiazine 1,1-dioxides 7. These products are derivatives of new or very rare heterocycles. CSIRO 2008.

A new series of selective COX-2 inhibitors: 5,6-diarylthiazolo[3,2-b][1,2,4]triazoles

A series of 5,6-diarylthiazolo[3,2-b][1,2,4]triazoles was prepared for evaluation of potency and selectivity against human COX-1 and COX-2 enzymes. This lead to the discovery of L-768,277, a potent and selective COX-2 inhibitor that also demonstrated good in vivo activity.

1-Dimethylcarbamyl-3-branched alkyl-1,2,4-triazol-5-yl-(N-substituted) sulfonamides and use as insecticides

Triazolylsulfonamides of a limited class are substantially non-phytotoxic and are useful as insecticides. For example 1-N,N-dimethylcarbamyl-3-tert.butyl-1,2,4-triazol-5-yl-N,N-dimethylsulfonamide is effective in aphid control, both by foliar application and systemically.