59694-11-0Relevant academic research and scientific papers
Highly enantioselective hydrogenation of 1-alkylvinyl benzoates: A simple, nonenzymatic access to chiral 2-alkanols
Kleman, Patryk,González-Liste, Pedro J.,García-Garrido, Sergio E.,Cadierno, Victorio,Pizzano, Antonio
, p. 16209 - 16212 (2013)
Going chiral! Highly enantioselective catalytic hydrogenations of enol esters 1 by using a Rh catalyst bearing a P?￡?OP ligand are described (see scheme; NBD=norbornadiene). The catalytic system has a broad scope and allows the preparation of a wide range of chiral esters 2 bearing diverse alkyls or a benzyl group with high enantioselectivities. These esters can easily be converted in highly enantioenriched 2-alkanols. Copyright
