5972-66-7Relevant academic research and scientific papers
Steroidal imidazole 1 carboxylic acid esters
Fahrenholtz,Boris,Kennedy Jr,Kierstead
, p. 337 - 342 (1974)
A variety of steroidal esters of imidazole 1 carboxylic acid and related acids was prepared by reaction of the steroidal alcohol with N,N' carbonyldiimidazole or by displacement of phenol from steroid phenylcarbonates. One compound, 21c (the imidazole 1 carboxylate of 19 norethisterone), was found to have an interesting separation of progestational from androgenic activity.
Synthesis of 13-alkyl-gon-4-ones
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, (2008/06/13)
The preparation of 13-methylgon-4-enes and novel 13-polycarbonalkylgon-4-enes by a new total synthesis is described. 13-Alkylgon-4-enes having progestational, anabolic and androgenic activities are prepared by forming a tetracylic gonane structure unsaturated in the 1,3,5(10),9(11) and 14-positions, selectively reducing in the B- and C-rings, and converting the aromatic A-ring compounds so-produced to gon-4-enes by Birch reduction and hydrolysis.
