Journal of Medicinal Chemistry p. 337 - 342 (1974)
Update date:2022-08-04
Topics:
Fahrenholtz
Boris
Kennedy Jr
Kierstead
A variety of steroidal esters of imidazole 1 carboxylic acid and related acids was prepared by reaction of the steroidal alcohol with N,N' carbonyldiimidazole or by displacement of phenol from steroid phenylcarbonates. One compound, 21c (the imidazole 1 carboxylate of 19 norethisterone), was found to have an interesting separation of progestational from androgenic activity.
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