59749-23-4 Usage
Uses
Used in Pharmaceutical Research:
1-(3,4-dichlorobenzyl)-5-oxo-L-proline is used as a building block for the synthesis of novel drugs and pharmacological agents. Its unique chemical structure and potential biological activity make it a valuable compound for the development of new therapeutics targeting various medical conditions.
Used in Cancer Treatment Research:
In the field of oncology, 1-(3,4-dichlorobenzyl)-5-oxo-L-proline is used as a potential therapeutic agent for the treatment of various types of cancer. Its chemical properties allow for the exploration of its effects on cancer cell growth and proliferation, as well as its potential to be incorporated into novel anticancer drugs.
Used in Inflammation and Infectious Disease Research:
1-(3,4-dichlorobenzyl)-5-oxo-L-proline is also used in the study of inflammation and infectious diseases. Its potential to modulate immune responses and target specific pathways involved in these conditions makes it a promising candidate for the development of new treatments.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 1-(3,4-dichlorobenzyl)-5-oxo-L-proline is used as an important target for further study and exploration. Its unique chemical structure and potential biological activity provide opportunities for the discovery of new drug candidates and therapeutic strategies.
Check Digit Verification of cas no
The CAS Registry Mumber 59749-23-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,9,7,4 and 9 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 59749-23:
(7*5)+(6*9)+(5*7)+(4*4)+(3*9)+(2*2)+(1*3)=174
174 % 10 = 4
So 59749-23-4 is a valid CAS Registry Number.
59749-23-4Relevant academic research and scientific papers
Synthesis and identification of chiral aminomethylpiperidine carboxamides as inhibitor of collagen induced platelet activation
Anil Kumar,Misra, Ankita,Siddiqi, Tanveer Irshad,Srivastava, Stuti,Jain, Manish,Bhatta, Rabi Sankar,Barthwal, Manoj,Dikshit, Madhu,Dikshit, Dinesh K.
, p. 456 - 472 (2014/06/09)
A series of chiral lactam carboxamides of aminomethylpiperidine were synthesized and investigated for the collagen induced in vitro anti-platelet efficacy and collagen plus epinephrine induced in vivo pulmonary thromboembolism. The compound 31a (30 μM/kg) displayed a remarkable antithrombotic efficacy (60% protection) which was sustained for more than 24 h and points to its excellent bioavailability. The compounds 31a (IC50 = 6.6 μM) and 32a (IC50 = 37 μM), as well as their racemic mixture 28i (IC50 = 16 μM) significantly inhibited collagen-induced human platelet aggregation in vitro. Compound 34c displayed dual mechanism of action against both collagen (IC50 = 3.3 μM) and U46619 (IC50 = 2.7 μM) induced platelet aggregation. The pharmacokinetic study of 31a indicated very faster absorption, prolonged and constant systemic exposure and thereby exhibiting better therapeutic response.
