597553-90-7Relevant academic research and scientific papers
Palladium-catalyzed intermolecular α-arylation of N-protected 2-piperidinones
Cossy, Janine,de Filippis, Arnault,Gomez Pardo, Domingo
, p. 3037 - 3039 (2003)
(Matrix presented) The α-arylation of the zinc enolate of N-protected 2-piperidinones with aryl bromides in the presence of a palladium catalyst is described as a general method.
Base Effect on the Palladium Catalyzed α-Arylation of N-Benzyl-2-Piperidinones
Cossy, Janine,De Filippis, Arnault,Gomez Pardo, Domingo
, p. 2171 - 2174 (2003)
A very simple method for obtaining α-arylated N-benzyl-2- piperidinones in high yields is described. The use of s-BuLi as the base and Pd(dba)2 as the catalyst are the key factors.
Palladium-catalyzed α-arylation of N-protected 2-piperidinones
Filippis, Arnault de,Pardo, Domingo Gomez,Cossy, Janine
, p. 9756 - 9768 (2007/10/03)
A very simple method for obtaining α-arylated N-protected 2-piperidinones in high yield is described. The use of ZnCl2 and Pd(dba)2 and the nature of the base are the key factors.
