59774-16-2Relevant academic research and scientific papers
Synthesis and pharmacologic study of pyridazino[4,5-b]carbazoles
Landelle,Laduree,Cugnon de Sevricourt,Robba
, p. 2679 - 2682 (2007/10/02)
Cyclization reaction of hydrazine with carbazole-2,3-methyl dicarboxylates gave 1,4-dioxo-1,2,3,4-tetrahydropyridazino[4,5-b]carbazoles. Chlorodehydroxylation provided 1,4-dichloropyridazino[4,5-b]carbazoles and nucleophilic substitution gave 1,4-dialkoxy pyridazino[4,5-b]carbazoles. These compounds were tested for cytotoxic activity against L1210 leukemia in mice.
Pyridazinocarbazole: Synthese et Etude des Spectres de Resonance Magnetique Nucleaire
Lancelot, Jean-Charles,Landelle, Henriette,Robba, Max
, p. 902 - 908 (2007/10/02)
The acid anhydrides (5-7) were obtained by treatment of corresponding 2,3-carbazole-dicarboxylic acids (2-4) with acetic anhydride.Friedel-Crafts reaction of these anhydrides with benzene or toluole gave either 3-aroylcarbazole-2-carboxylic acids (8-11) o
