59774-26-4

Upstream product

• 124-41-4 sodium methylate 
• 59774-21-9 6H-dichloro-1,4 ethyl-5 pyridazino<4,5-b>carbazole 
• 59774-16-2 ethyl-5 dioxo-1,4 tetrahydro-1,2,3,4 6H-pyridazino<4,5-b>carbazole 
• 59774-13-9 diester methylique de l'acide ethyl-1 carbazoledicarboxylique-2,3 

Relevant academic research and scientific papers

Synthesis and pharmacologic study of pyridazino[4,5-b]carbazoles

Cyclization reaction of hydrazine with carbazole-2,3-methyl dicarboxylates gave 1,4-dioxo-1,2,3,4-tetrahydropyridazino[4,5-b]carbazoles. Chlorodehydroxylation provided 1,4-dichloropyridazino[4,5-b]carbazoles and nucleophilic substitution gave 1,4-dialkoxy pyridazino[4,5-b]carbazoles. These compounds were tested for cytotoxic activity against L1210 leukemia in mice.