59782-86-4 Usage
Uses
Used in Pharmaceutical Industry:
2-Chloro-5-Iodoniconitic acid is used as a chemical precursor for the synthesis of various pharmaceutical compounds. Its reactivity and the presence of halogens make it a valuable component in the development of new drugs.
Used in Agrochemical Industry:
In the agrochemical industry, 2-Chloro-5-Iodoniconitic acid is used as a starting material for the production of certain agrochemicals. Its chemical properties allow for the creation of effective products for agricultural applications.
Used in Materials Science:
2-Chloro-5-Iodoniconitic acid is employed in materials science as a component in the development of new materials with specific properties. Its reactivity and the presence of halogens contribute to the creation of innovative materials for various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 59782-86-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,9,7,8 and 2 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 59782-86:
(7*5)+(6*9)+(5*7)+(4*8)+(3*2)+(2*8)+(1*6)=184
184 % 10 = 4
So 59782-86-4 is a valid CAS Registry Number.
InChI:InChI=1/C6H3ClINO2/c7-5-4(6(10)11)1-3(8)2-9-5/h1-2H,(H,10,11)
59782-86-4Relevant academic research and scientific papers
Orally active ghrelin receptor inverse agonists and their actions on a rat obesity model
Takahashi, Bitoku,Funami, Hideaki,Iwaki, Takehiko,Maruoka, Hiroshi,Shibata, Makoto,Koyama, Makoto,Nagahira, Asako,Kamiide, Yoshiyuki,Kanki, Satomi,Igawa, Yoshiyuki,Muto, Tsuyoshi
, p. 4792 - 4803 (2015/08/03)
A series of 2-alkylamino nicotinamide analogs was prepared as orally active ghrelin receptor (ghrelinR) inverse agonists. Starting from compound 1, oral bioavailability was improved by modifying metabolically unstable sites and reducing molecular weight. Brain-permeable compound 33 and compound 24 with low brain permeability were tested in rat models of obesity; 30 mg/kg of compound 33 suppressed weight gain. PK/PD analysis revealed that the anti-obesity effect of ghrelinR inverse agonists depends on their brain concentrations.
