2-Chloro-5-iodonicotinic acid

Base Information

Chemical Name:2-Chloro-5-iodonicotinic acid
CAS No.:59782-86-4
Molecular Formula:C6H3ClINO2
Molecular Weight:283.453
Hs Code.:2933399090
DSSTox Substance ID:DTXSID60504938
Wikidata:Q82359727
Mol file:59782-86-4.mol

Synonyms:2-Chloro-5-iodonicotinic acid;59782-86-4;2-chloro-5-iodopyridine-3-carboxylic acid;SCHEMBL1584884;DTXSID60504938;MFCD08276959;AKOS005069371;CS-0157380;FT-0679987;EN300-192332;I11277;A869119;10Z-0716;J-508851

Suppliers and Price of 2-Chloro-5-iodonicotinic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
2-Chloro-5-iodonicotinic acid
500 mg
$ 295.00

Matrix Scientific
2-Chloro-5-iodonicotinic acid >95%
1g
$ 300.00

Matrix Scientific
2-Chloro-5-iodonicotinic acid >95%
500mg
$ 195.00

Matrix Scientific
2-Chloro-5-iodonicotinic acid >95%
5g
$ 500.00

Crysdot
2-Chloro-5-iodonicotinicacid 95+%
5g
$ 396.00

Crysdot
2-Chloro-5-iodonicotinicacid 95+%
25g
$ 1485.00

Crysdot
2-Chloro-5-iodonicotinicacid 95+%
10g
$ 743.00

Chemenu
2-Chloro-5-iodonicotinicacid 95%
10g
$ 701.00

Chemenu
2-Chloro-5-iodonicotinicacid 95%
25g
$ 1403.00

Chemenu
2-Chloro-5-iodonicotinicacid 95%
5g
$ 374.00

Total 17 raw suppliers

Chemical Property of 2-Chloro-5-iodonicotinic acid

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:221-224°C
Refractive Index:1.684
Boiling Point:391.014°C at 760 mmHg
Flash Point:190.278°C
PSA：50.19000
Density:2.194g/cm³
LogP:2.03780
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:282.88970
Heavy Atom Count:11
Complexity:167

Purity/Quality:

97% ^*data from raw suppliers

2-Chloro-5-iodonicotinic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C=NC(=C1C(=O)O)Cl)I

Technology Process of 2-Chloro-5-iodonicotinic acid

There total 3 articles about 2-Chloro-5-iodonicotinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 390360-97-1
2-hydroxy-5-iodonicotinic acid

: 59782-86-4
2-chloro-5-iodonicotinic acid

Guidance literature:: With thionyl chloride; In N,N-dimethyl-formamide; at 70 ℃; for 4h;
DOI:10.1016/j.bmc.2015.05.047

Reference yield:

: 609-71-2
2-hydroxy-3-carboxypyridine

: 59782-86-4
2-chloro-5-iodonicotinic acid

Guidance literature:: Multi-step reaction with 2 steps

1: N-iodo-succinimide / N,N-dimethyl-formamide / 21 h / 20 - 50 °C / Darkness

2: thionyl chloride / N,N-dimethyl-formamide / 4 h / 70 °C

With N-iodo-succinimide; thionyl chloride; In N,N-dimethyl-formamide;
DOI:10.1016/j.bmc.2015.05.047