598-82-3 Hazards Identification
Pictogram(s):
Signal:
Danger
GHS Hazard Statements:
H315 (89.99%): Causes skin irritation [Warning Skin corrosion/irritation]
H318 (91.66%): Causes serious eye damage [Danger Serious eye damage/eye irritation]
Precautionary Statement Codes:
P264, P264+P265, P280, P302+P352, P305+P354+P338, P317, P321, P332+P317, and P362+P364
Hazard Classes and Categories:
Skin Irrit. 2 (89.99%)
Eye Dam. 1 (91.66%)
Skin corrosion/irritation - Category 1
Serious eye damage/eye irritation - Category 1
Hazards Summary:
Corrosive to skin; [Quick CPC] A skin and respiratory tract irritant; Corrosive to eyes; [ICSC] Causes burns to skin and eyes; Vapors cause eye and mucous membrane irritation and can cause coughing and difficulty breathing; [CHRIS] Safe when used as a flavoring agent in food; [JECFA] Corrosive to rabbit skin, mildly irritating to guinea pig skin, and not irritating to pig skin; Not sensitizing in a study of guinea pigs; A 13-week oral study of rats produced a NOAEL of 500 mg/kg/day (highest tested dose); Studies on reproductive and developmental toxicity not considered necessary because lactic acid is a product of human intermediary metabolism; [EPA ChAMP] A skin and strong eye irritant; [Aldrich MSDS]
598-82-3 Usage
Uses
Used in Pharmaceutical Industry:
DL-Lactic acid is used as an excipient for the formulation of pharmaceutical products, such as tablets and injections, due to its ability to enhance solubility and stability of active ingredients.
Used in Food and Beverage Industry:
DL-Lactic acid is used as a flavor enhancer and preservative in the food and beverage industry, providing a tangy taste and extending the shelf life of products.
Used in Cosmetics and Personal Care Industry:
DL-Lactic acid is used as a humectant and exfoliant in cosmetics and personal care products, helping to maintain skin moisture and promote cell turnover.
Used in Biodegradable Polymers:
DL-Lactic acid is used as a monomer in the production of biodegradable polymers, such as polylactic acid (PLA), which are used in packaging materials and medical devices due to their eco-friendly properties.
Used in Animal Nutrition:
DL-Lactic acid is used as a feed additive in the animal nutrition industry to improve animal health and performance by providing an energy source and supporting gut health.
Used in Sports Nutrition:
DL-Lactic acid is used as an ingredient in sports nutrition products, such as energy drinks and supplements, to help replenish energy levels and support muscle recovery after intense exercise.
Check Digit Verification of cas no
The CAS Registry Mumber 598-82-3 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,9 and 8 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 598-82:
(5*5)+(4*9)+(3*8)+(2*8)+(1*2)=103
103 % 10 = 3
So 598-82-3 is a valid CAS Registry Number.
InChI:InChI=1/C3H6O3/c1-2(4)3(5)6/h2,4H,1H3,(H,5,6)/p-1/t2-/m1/s1
598-82-3Relevant academic research and scientific papers
S-2-Hydroxyacylglutathione-Derivatives: Enzymatic Preparation, Purification and Characterisation
Clelland, James D.,Thornalley, Paul J.
, p. 3009 - 3016 (2007/10/02)
S-2-Hydroxyacylglutathione derivatives have been prepared by enzymatic synthesis from α-oxoaldehydes and reduced glutathione in the presence of glyoxalase I.S-D-Lactoylglutathione, S-D-mandelylglutathione, S-glycolylglutathione and S-L-glyceroylglutathione were prepared from methylglyoxal, phenylglyoxal, glyoxal and hydroxypyruvaldehyde, respectively.They were purified by ion exchange chromatography on Dowex 1 on a gram scale.Analytical data and re-evaluated extinction coefficients for these compounds are presented.The method described provides a reliable, large-scale procedure for the preparation and purification of S-acylglutathiones of increasing biological and pharmacological interest.
Photosensitized NAD(P)H Regeneration Systems; Application in the Reduction of Butan-2-one, Pyruvic, and Acetoacetic Acids and in the Reductive Amination of Pyruvic and Oxoglutaric Acid to Amino Acid
Mandler, Daniel,Willner, Itamar
, p. 805 - 812 (2007/10/02)
The photosensitized formation of NAD(P)H by enzyme-catalysed processes has been accomplished.With Ru(bpy)32+ as sensitizer, methyl viologen, MV2+ as primary electron acceptor, and (NH4)3EDTA or 2- mercaptoethanol, NADPH is formed in the presence of ferredoxin NADP+-reductase as enzyme catalyst.Zinc(II)meso-tetramethylpyridiniumporphyrin, ZnTMPy4+ is used as sensitizer for the photoinduced production of NADH using the same components and lipoamide dehydrogenase as enzyme catalyst.The photoinduced NAD(P)H regeneration systems have been coupled to secondary enzyme-catalysed processes such as the reduction of butan-2-one to butan-2-ol, pyruvic acid to lactic acid, acetoacetic acid to β-hydroxybutyric acid, as well as to the reductive amination of pyruvic acid to alanine and of α-oxoglutaric acid to glutamine acid.The products exhibit high optical purity and the enzymes and the coenzymes show high turnover numbers and stability.
