59802-10-7

Usage

Properties

1. Chemical name: 2-[5-ethyl-5-(hydroxymethyl)-1,3-dioxan-2-yl]-2-methylpropan-1-ol
2. Also known as: ethylidene-l-methyl-2-methylpropanol
3. Molecular formula: C11H22O3
4. Physical state: colorless liquid
5. Odor: floral, fruity
6. Common uses: manufacturing of perfumes and fragrances, solvent, raw material for chemical synthesis

Physical state

colorless liquid

Odor

floral, fruity

Uses

manufacturing of perfumes and fragrances, solvent, raw material for chemical synthesis

Caution

handle with care as it can be harmful if ingested or inhaled, may cause irritation to skin and eyes

Upstream product

• 597-31-9 2,2-dimethyl-3-hydroxypropionaldehyde 
• 77-99-6 1,1,1-tri(hydroxymethyl)propane 

Downstream Products

• 558483-51-5 C₃₁H₄₄N₂O₁₀ 
• 87320-05-6 5-ethyl-5-(hydroxymethyl)-β,β-dimethyl-1,3-dioxan-2-ethanol diacrylate 

Relevant academic research and scientific papers

POLYETHERPOLYOL AND PRODUCTION METHOD THEREOF

PROBLEM TO BE SOLVED: To provide a method of efficiently producing a polyetherpolyol, and a novel polyetherpolyol compound obtained by the production method. SOLUTION: A compound represented by the specified general formula (1) is subjected to hydrogenation reduction in the presence of a hydrogenation catalyst to produce a polyetherpolyol represented by the specified general formula (2). In the formulas (1) and (2), R1 to R5 may be identical to or different from each other and represent C1-6 linear or branched alkyl groups. COPYRIGHT: (C)2016,JPOandINPIT

ESTER COMPOUND AND METHOD FOR PRODUCING THE SAME

PROBLEM TO BE SOLVED: To provide an ester compound that can be synthesized easily from a variety of carboxylic acid compounds, is hard to crystallize and volatilize, and has an excellent viscosity index. SOLUTION: The present invention provides an ester compound represented by general formula (1) where R1s independently represent C1-C25 aliphatic groups, aralkyl groups or aryl groups, R11, R12 and R13 independently represent C1-C10 alkyl groups. SELECTED DRAWING: None COPYRIGHT: (C)2016,JPOandINPIT

POLYOL-ETHER COMPOUND AND METHOD FOR PRODUCING THE SAME

A method for producing a polyol-ether compound, wherein a compound represented by the following formula (1) is subjected to hydrogenation reduction in the presence of a hydrogenation catalyst to obtain a polyol-ether compound having a skeleton represented by the following formula (2): wherein R1 and R2, which may be the same as or different from each other, each represent a linear or branched alkyl group having 1 to 6 carbon atoms; and R3 represents a linear or branched alkyl group having 1 to 6 carbon atoms or a hydroxymethyl group.

Macroporous hydrogels upregulate osteogenic signal expression and promote bone regeneration

The objective of this work was to investigate the effects of macroporous hydrogel architecture on the osteogenic signal expression and differentiation of human mesenchymal stem cells (hMSCs). In particular, we have proposed a tissue engineering approach for orbital bone repair based on a cyclic acetal biomaterial formed from 5-ethyl-5-(hydroxymethyl)-β,β-dimethyl-1,3- dioxane-2-ethanol diacrylate (EHD) and poly(ethylene glycol) diacrylate (PEGDA). The EHD monomer and PEGDA polymer may be fabricated into macroporous EH-PEG hydrogels by radical polymerization and subsequent porogen leaching, a novel technique for hydrophilic gels. We hypothesized that EH-PEG hydrogel macroporosity facilitates intercellular signaling among hMSCs. To investigate this phenomenon, hMSCs were loaded into EH-PEG hydrogels with varying pore size and porosity. The viability of hMSCs, the expression of bone morphogenetic protein-2 (BMP-2), BMP receptor type 1A, and BMP receptor type 2 by hMSCs, and the differentiation of hMSCs were then assessed. Results demonstrate that macroporous EH-PEG hydrogels support hMSCs and that this macroporous environment promotes a dramatic increase in BMP-2 expression by hMSCs. This upregulation of BMP-2 expression is associated by a more rapid hMSC differentiation, as measured by alkaline phosphatase expression. Altering hMSC interactions with the EH-PEG hydrogel surface, by the addition of fibronectin, did not appear to augment BMP-2 expression. We therefore speculate that EH-PEG hydrogel macroporosity facilitates autocrine and paracrine signaling by localizing endogenously expressed factors within the hydrogel's pores and thus promotes hMSC osteoblastic differentiation and bone regeneration.

PROCESS FOR PRODUCTION OF FLAKE-LIKE DRIED 2-(5-ETHYL-5-HYDROXYMETHYL-1,3-DIOXAN-2-YL)-2-METHYLPROPAN-1-OL

A method for producing flake-like dried DOG by making DOG containing from 10 to 50 % by mass of a liquid go through a continuous melt-drying step of a specified condition and then making it go through, as a next step, a vacuum-drying step of a specified condition or a ventilation-drying step of a specified condition while holding a molten state thereof, to obtain DOG in which the liquid in DOG is reduced to not more than 0.5 % by mass (dried DOG), and flaking the obtained dried DOG in a flake production step.

Maleimido-bearing compounds resin composition containing the same and cured articles thereof

The present invention provides (meth)acrylate compounds bearing a specific maleimide group and resin compositions containing said compounds that can be cured by irradiation of light in a practical dose even when a photoinitiator is not used or used in a smaller amount than that of the prior art, and cured articles of the resin compositions.