59846-34-3Relevant academic research and scientific papers
Enantioselective radical reactions: Stereoselective aldol synthesis from cyclic ketones
Sibi, Mukund P.,Nad, Sukanya
, p. 9231 - 9234 (2008/12/22)
(Chemical Equation Presented) Radicalized aldols: Enones with a fixed s-cis geometry can undergo enantioselective radical reactions. The synthesis of aldol products derived from cyclic ketones in excellent yields and enantioselectivity demonstrates that s-cis-enones are excellent substrates for radical reactions. A tentative model to explain the stereochemical outcome of the reaction consists of nucleophilic radical addition to the si face (see picture).
