59871-23-7Relevant academic research and scientific papers
Hydroxysulfenylation of electron-deficient alkenes through an aerobic copper catalysis
Xi, Hui,Deng, Bicheng,Zong, Zhenzhen,Lu, Shenglin,Li, Zhiping
, p. 1180 - 1183 (2015)
A copper-catalyzed hydroxysulfenylation of α,β-unsaturated esters/amides is reported. The method presents a selective and efficient synthesis of β-hydroxysulfides bearing electron-withdrawing groups. The synthetic utility of this method is demonstrated by the concise synthesis of the anticancer drug bicalutamide.
