59943-16-7

Basic information

• Product Name: benzyl 9-O-(α-benzyloxycarbonyl)phenylacetylclavulanate
• Synonyms: benzyl 9-O-(α-benzyloxycarbonyl)phenylacetylclavulanate
• CAS NO: 59943-16-7
• Molecular Weight: 541.557
• Mol File: 59943-16-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: benzyl 9-O-(α-benzyloxycarbonyl)phenylacetylclavulanate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl 9-O-(α-benzyloxycarbonyl)phenylacetylclavulanate(59943-16-7)
• EPA Substance Registry System: benzyl 9-O-(α-benzyloxycarbonyl)phenylacetylclavulanate(59943-16-7)

Safety Data

• Hazardous Substances Data: 59943-16-7(Hazardous Substances Data)

Upstream product

• 25774-02-1 monobenzyl phenylmalonate 
• 57943-84-7 Benzyl Clavulanate 

Downstream Products

• 91022-13-8 9-O-clavulanic acid 

Relevant articles and documents

Clavulanic Acid and its Derivatives. Structure Elucidation of Clavulanic Acid and the Preparation of Dihydroclavulanic Acid, Isoclavulanic acid, Esters and Related Oxidation Products

Clavulanic acid, a novel β-lactamase inhibitor from Streptomyces clavuligerus, has been shown to be Z-(2R,5R)-3-(β-hydroxyethylidene)-7-oxo-4-oxa-1-azabicycloheptane-2-carboxylic acid (1).The structure and absolute stereochemistry was confirmed by X-ray analysis of the p-nitrobenzyl and p-bromobenzyl esters, (14) and (15).The conversion of clavulanic acid into a variety of esters and acyl derivatives is described.An account of its isomerisation to the E isomer (30) and the formation of an oxetane (45) as a by-product of the photolysis of the phenacyl ester (18) is given.The reduction and oxidation of acid (1) under a variety of conditions has also been examined in detail.