59962-90-2Relevant academic research and scientific papers
Tandem Synthesis of 2-Carboxybenzofurans via Sequential Cu-Catalyzed C-O Coupling and Mo(CO)6-Mediated Carbonylation Reactions
Mo, Qinliang,Sun, Nan,Jin, Liqun,Hu, Baoxiang,Shen, Zhenlu,Hu, Xinquan
, p. 11490 - 11500 (2020/10/12)
A modular tandem synthesis of 2-carboxybenzofurans from 2-gem-dibromovinylphenols has been established based on a sequence of Cu-catalyzed intramolecular C-O coupling and Mo(CO)6-mediated intermolecular carbonylation reactions. This protocol allowed one-step access to a broad variety of functionalized benzofuran-2-carboxylic acids, esters, and amides in good to excellent yields under Pd- and CO gas-free conditions.
Microwave-assisted synthesis of 5-arylbenzofuran-2-carboxylates via Suzuki coupling using a 2-quinolinealdoxime-Pd(II)-complex
Dawood, Kamal M.,Farag, Ahmad M.,El-Deftar, Moteaa M.,Gardiner, Michael,Abdelaziz, Hatem A.
, p. 210 - 226 (2013/06/27)
A new quinoline-based Pd(II)-complex was synthesized and its structure was established by single crystal X-ray analysis. Applications of the obtained complex as a precatalyst in Suzuki-Miyaura C-C cross-coupling reactions of 4-bromoacetophenone and 5-bromobenzofuran-2-carboxylate esters with several aryl- and heteroarylboronic acids were investigated. The catalytic activity of the Pd(II)-precatalyst under microwave irradiating conditions was evaluated. ARKAT-USA, Inc.
2,3-Dihydro benzofuran carboxamides
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, (2008/06/13)
Certain 5-(or 4-)substituted 2,3-dihydro-N-(2-propenyl)-2-benzofurancarboxamides, useful as lipogenesis inhibitors in mammals.
Inhibition of lipogenesis
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, (2008/06/13)
Lipogenesis in mammals is inhibited by benzofurancarboxylic acids substituted on the aromatic ring by one of certain moieties, and the 2,3-dihydro counterparts thereof.
