1761-63-3

Basic information

• Product Name: 2-hydroxy-5-phenylbenzaldehyde
• Synonyms: 2-hydroxy-5-phenylbenzaldehyde
• CAS NO: 1761-63-3
• Molecular Weight: 198.221
• Mol File: 1761-63-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-hydroxy-5-phenylbenzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2-hydroxy-5-phenylbenzaldehyde(1761-63-3)
• EPA Substance Registry System: 2-hydroxy-5-phenylbenzaldehyde(1761-63-3)

Safety Data

• Hazardous Substances Data: 1761-63-3(Hazardous Substances Data)

Upstream product

• 67-66-3 chloroform 
• 92-69-3 4-Phenylphenol 

Downstream Products

• 102183-99-3 phenyl(5-phenylbenzofuran-2-yl)methanone 
• 102183-06-2 (4-chloro-phenyl)-(5-phenyl-benzofuran-2-yl)-ketone 
• 82305-05-3 2,2-dimethyl-6-phenyl-2H-chromene 
• 803688-28-0 3-([5-(t-butyl)-2-hydroxyphenyl]iminomethyl)[1,1'-biphenyl]-4-ol 
• 796047-10-4 2-benzyloxy-5-phenylbenzaldehyde 
• 1006900-81-7 4,4a-dihydro-8-phenylpyrano[4,3-b]chromen-1(3H)-one 
• 1169882-38-5 6-phenylbenzo[e][1,2,3]oxathiazine 2,2-dioxide 
• 73108-75-5 6-phenyl-2H-chromen-2-one 
• 1268833-78-8 3-(5,6-dihydro-4H-1,3-oxazin-2-yl)-[1,1'-biphenyl]-4-ol 
• 1268833-91-5 7-phenyl-3,3a-dihydro-1H-benzo[e]pyrrolo[2,1-b][1,3]oxazin-9-(2H)-one 
• 1510865-12-9 2,3,7-triphenylbenzo[b]oxepine 

Relevant articles and documents

Selective Syntheses Using Cyclodextrin as Catalyst. 1. Control of Orientation in the Attack of Dichlorocarbene at Phenolates

4-Hydroxybenzaldehydes, 2,4-dihydroxybenzaldehyde, and 4-(dichloromethyl)-2,5-cyclohexadienones were synthesized in virtually 100percent selectivities and high yields from the corresponding phenols and chloroform in alkaline aqueous solutions by using α- or β-cyclodextrin (α- or β-CD) as catalyst.The regulation of the molar ratio of chloroform to CD below unity throughout the reaction time, by controlling the rate of addition of chloroform, was definitely required to attain high selectivity.Under these conditions, dichlorocarbene, prepared in situ from chloroform and sodium hydroxide, attacked overwhelmingly at the para carbon of phenols with almost perfect suppression of the reaction at the ortho carbon.The structure of the ternary molecular complex composed of β-CD, chloroform, and phenol, formed in the reaction mixture for the selective synthesis of 4-hydroxybenzaldehyde, was determined by NMR spectroscopy.The selective catalysis by CDs was attributed to the regulation of molecular conformation of phenols with respect to chloroform, and thus to dichlorocarbene, in the ternary complex.