59968-26-2

Basic information

• Product Name: 1,3-dimethoxy-5,6-dimethylbenzene
• Synonyms: 1,3-dimethoxy-5,6-dimethylbenzene
• CAS NO: 59968-26-2
• Molecular Weight: 166.22
• Mol File: 59968-26-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1,3-dimethoxy-5,6-dimethylbenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-dimethoxy-5,6-dimethylbenzene(59968-26-2)
• EPA Substance Registry System: 1,3-dimethoxy-5,6-dimethylbenzene(59968-26-2)

Safety Data

• Hazardous Substances Data: 59968-26-2(Hazardous Substances Data)

Upstream product

• 126-81-8 dimedone 
• 149-73-5 trimethyl orthoformate 
• 26050-72-6 (3,5-dimethoxybenzyl)trimethylammonium chloride 
• 67-56-1 methanol 
• 95-65-8 3,4-Dimethylphenol 
• 26050-73-7 N,N-Dimethyl-2,4-dimethoxy-6-methylbenzylamine 
• 7149-90-8 2,4-dimethoxy-6-methyl-benzaldehyde 
• 6652-32-0 3,5-dimethoxybenzylchloride 
• 35236-36-3 1,5-diacetoxy-2,3-dimethylbenzene 
• 77-78-1 dimethyl sulfate 
• 20361-26-6 4-Chlor-3.4-dimethylcyclohexa-2.5-dien-1-on 

Downstream Products

• 1118905-13-7 C₁₉H₂₅BrO₂S 
• 7743-14-8 4,6-dihydroxy-2,3-dimethylacetophenone 
• 124492-52-0 3,6-dihydro-1,5-dimethoxy-2,3-dimethylbenzene 
• 527-55-9 4,5-dimethylresorcinol 

Relevant articles and documents

Facile synthesis of α-iodo carbonyl compounds and α-iodo dimethyl ketals using molecular iodine and trimethylorthoformate

A novel and direct method for the synthesis of α-iodo ketones and α-iodo dimethyl ketals from acetophenones using iodine and trimethylorthoformate under neutral conditions is described herein.

Electrophilic Chlorination of 4-Methylphenols with Molecular Chlorine. Synthesis of Dimethoxy Aromatics by Methanolysis of 4-Chloro-4-methylcyclcohexa-2,5-dienones

The chlorination of p-cresol (1a), 2,4-dimethylphenol (1b), 3,4-dimethylphenol (1c), 2,4,5-trimethylphenol (1d), 2,4,6-trimethylphenol (1e) and the various possible mono- and dichloro derivatives of these phenols (3a-d, 6a and 6 c) with molecular chlorine was investigated in dichloromethane or dimethyl formamide solution.The 2,6-substituted p-cresol derivatives all give quantitative yields of 4-chloro-4-methylcyclohexa-2,5-dienones (5b, 5d, 7a, 7c and 2e), whereas the less substituted p-cresol derivatives give a 20-25percent yield of corresponding 4-chloro-4-methylcyclohexa-2,5-dienones (2a-d, 5a and 5c), the other products being chlorinated phenols.Treatment of 4-chloro-4-methylcyclohexa-2,5-dienones with at least one of the double bonds of the ring unsubstituted (2a-c and 4a) with methanol gave a quantitative yield of a 1,3-dimethoxybenzene derivative (9a-c and 10), whereas similar treatment of 4-chloro-2,4,5-trimethylcyclohexa-2,5-dienone (2d) gave 5-methoxy-2,3-dimethylbenzyl methyl ether (11).Treatment of the other 4-chlorodienones with methanol gave the corresponding 4-methoxydienones.Electrophilic chlorination of certain p-cresol derivatives followed by methanolysis hence is a facile although low-yield method for 3-methoxylation or selective side chain oxidation of these p-cresol derivatives.