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6α,11α-dihydroxypregn-4-ene-3,20-dione is a steroidal compound characterized by the presence of two hydroxyl groups at the 6α and 11α positions on the pregnane ring structure. This molecule features a four-carbon ring (A ring), a five-carbon ring (B ring), and a six-carbon ring (C ring), with a ketone group at the 3-position and another ketone group at the 20-position. The presence of these functional groups gives the molecule unique chemical properties and potential biological activities. It is a derivative of the pregnane family of steroids, which are known for their diverse roles in various physiological processes, including hormone regulation and immune response. The specific arrangement of hydroxyl and ketone groups in 6α,11α-dihydroxypregn-4-ene-3,20-dione may influence its solubility, reactivity, and potential therapeutic applications.

600-49-7

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600-49-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 600-49-7 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,0 and 0 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 600-49:
(5*6)+(4*0)+(3*0)+(2*4)+(1*9)=47
47 % 10 = 7
So 600-49-7 is a valid CAS Registry Number.

600-49-7Downstream Products

600-49-7Relevant academic research and scientific papers

Microbial hydroxylation of hydroxyprogesterones and α-glucosidase inhibition activity of their metabolites

Choudhary, Muhammad Iqbal,Nasir, Muhammad,Khan, Shamsun N.,Atif, Muhammad,Ali, Rahat A.,Khalil, Syed M.,Atta-ur-Rahman

, p. 593 - 599 (2007)

Microbial transformation of 11α-hydroxyprogesterone (1) with Cunninghamella elegans, Gibberella fujikuroi, Fusarium lini, and Candida albicans yielded 11α,15α,16α-trihydroxypregn-4-ene-3,20-dione (3), 11α-hydroxy-5α-pregnane-3,20-dione (4), 6β,11α- dihydroxypregn-4-ene-3,20-dione(5), 11α-hydroxypregna-1,4-diene-3,20-dione (6), 11α,17β-dihydroxyandrost-4-en-3-one (7), and 11α,15α-dihydroxypregn-4-ene-3,20-dione (8). On the other hand, microbial transformation of 17α-hydroxyprogesterone (2) with Cunninghamella elegans and Fusarium Uni yielded 11α,17α- dihydroxypregn-4-ene-3,20-dione (9), and 17α-hydroxypregna-1,4-diene-3,20- dione (10). The structures of the metabolites 3-10 were deduced on the basis of spectroscopic methods. Compound 3 was identified as a new metabolite, which exhibited a promising inhibitory activity against the α-glucosidase enzyme.

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