6-Dehydrocortisol, also known as Hydrocortisone EP Impurity E, is a metabolite of Cortisol (H714615), a glucocorticoid hormone produced by the zona fasciculata of the adrenal gland. It plays a significant role in the body's response to stress and regulation of various physiological processes.
Used in Pharmaceutical Industry:
6-Dehydrocortisol is used as a research compound for the identification of Trp-371 as the main site of specific photoaffinity labeling of corticosteroid binding globulin. This helps in understanding the molecular mechanisms of corticosteroid action and the development of new therapeutic agents targeting corticosteroid receptors.
Used in Medical Research:
6-Dehydrocortisol is used as a biochemical marker in the study of adrenal gland function and the metabolism of Cortisol. It aids in the diagnosis and monitoring of various endocrine disorders and conditions related to the hypothalamic-pituitary-adrenal (HPA) axis.
Used in Pharmaceutical Industry:
6-Dehydrocortisol is used as a research compound for the identification of Trp-371 as the main site of specific photoaffinity labeling of corticosteroid binding globulin. This helps in understanding the molecular mechanisms of corticosteroid action and the development of new therapeutic agents targeting corticosteroid receptors.
Used in Medical Research:
6-Dehydrocortisol is used as a biochemical marker in the study of adrenal gland function and the metabolism of Cortisol. It aids in the diagnosis and monitoring of various endocrine disorders and conditions related to the hypothalamic-pituitary-adrenal (HPA) axis.
600-99-7
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Basic information
- Product Name: 6-Dehydrocortisol
- Synonyms: 6-Dehydrocortisol;Hydrocortisone EP Impurity E;Hydrocortisone impurity E (EP);11β,17,21-Trihydroxypregna-4,6-diene-3,20-dione
- CAS NO:600-99-7
- Molecular Formula: C21H28O5
- Molecular Weight: 360.44402
- EINECS: N/A
- Product Categories: Pharmaceuticals, Intermediates & Fine Chemicals, Steroids
- Mol File: 600-99-7.mol
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Chemical Properties
- Melting Point: 239-241 °C
- Boiling Point: 586°C at 760 mmHg
- Flash Point: 322.2°C
- Appearance: /
- Density: 1.31g/cm3
- Vapor Pressure: 3.59E-16mmHg at 25°C
- Refractive Index: 1.611
- Storage Temp.: Refrigerator
- Solubility: Dioxane (Slightly), DMSO (Slightly), Methanol (Slightly)
- PKA: 12.44±0.70(Predicted)
- CAS DataBase Reference: 6-Dehydrocortisol(CAS DataBase Reference)
- NIST Chemistry Reference: 6-Dehydrocortisol(600-99-7)
- EPA Substance Registry System: 6-Dehydrocortisol(600-99-7)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 600-99-7(Hazardous Substances Data)
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600-99-7 Usage
Check Digit Verification of cas no
The CAS Registry Mumber 600-99-7 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,0 and 0 respectively; the second part has 2 digits, 9 and 9 respectively.Calculate Digit Verification of CAS Registry Number 600-99:
(5*6)+(4*0)+(3*0)+(2*9)+(1*9)=57
57 % 10 = 7
So 600-99-7 is a valid CAS Registry Number.
InChI:InChI=1/C21H28O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h3-4,9,14-16,18,22,24,26H,5-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1
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6-Dehydrocortisol
