600143-38-2

Upstream product

• 75-16-1 methylmagnesium bromide 
• 600143-37-1 (3R,5R,8R,9RS)-5-(benzyloxypropyl)-8-tert-butyldimethylsilyloxy-3-phenyloxazolo[3,2-a]piperidine 
• 600143-36-0 (3R,8R,9RS)-5-(benzyloxypropyl)-8-tert-butyldimethylsilyloxy-3-phenyloxazolo[3,2-a]piperidine-5-carbonitrile 

Downstream Products

• 600143-41-7 (4R,6S,7R,10R)-7-tert-butyldimethylsilyloxy-6-methyl-octahydroquinolizidine-4-carbonitrile 
• 600143-40-6 (2S,3R,6R)-3-tert-butyldimethylsilyloxy-1-cyanomethyl-6-(3-hydroxypropyl)-2-methylpiperidine 
• 600143-43-9 (3R,4S,6R,10R)-6-ethynyl-3-tert-butyldimethylsilyloxy-4-methyl-octahydroquinolizidine 
• 600143-44-0 (3R,4S,6R,10R)-6-ethynyl-3-tert-butyldimethylsilyloxy-4-methyl-6-(phenylethynyl)octahydroquinolizidine 
• 600143-42-8 (3R,4S,6R,9aR)-3-(tert-Butyl-diphenyl-silanyloxy)-4-methyl-6-trimethylsilanylethynyl-octahydro-quinolizine 
• 600143-46-2 (1E,3R,4S,6R,10R)-3-tert-butyldimethylsilyloxy-6-(dec-1-enyl)-4-methyloctahydroquinolizidine 
• 600143-45-1 (3E,3R,4S,6R,10R)-3-tert-butyldimethylsilyloxy-6-(dec-3-en-1-ynyl)-4-methyloctahydroquinolizidine 
• 600143-47-3 (3R,4S,6R,10R)-3-tert-butyldimethylsilyloxy-6-decyl-4-methyloctahydroquinolizidine 
• 600143-39-3 (2S,3R,6R)-3-tert-butyldimethylsilyloxy-6-(3-hydroxypropyl)-2-methylpiperidine 

Relevant academic research and scientific papers

Enantioselective synthesis of clavepictine analogues and evaluation of their cytotoxic activity

Six analogues (labeled 27 to 32) of a cytotoxic alkaloid isolated from the tunicate Clavelina picta were synthesized from an acyl oxazolidine. The absolute stereochemistry of the targeted analogues derived from (R)-phenyl glycinol and the relative stereoc