60031-20-1Relevant academic research and scientific papers
In vivo structure-activity relationship studies support allosteric targeting of a dual specificity phosphatase
Korotchenko, Vasiliy N.,Saydmohammed, Manush,Vollmer, Laura L.,Bakan, Ahmet,Sheetz, Kyle,Debiec, Karl T.,Greene, Kristina A.,Agliori, Christine S.,Bahar, Ivet,Day, Billy W.,Vogt, Andreas,Tsang, Michael
, p. 1436 - 1445 (2014/07/21)
Dual specificity phosphatase 6 (DUSP6) functions as a feedback attenuator of fibroblast growth factor signaling during development. In vitro high throughput chemical screening attempts to discover DUSP6 inhibitors have yielded limited success. However, in
